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Decreased LAG3 expression on T effector cells and regulatory T cells in SAA.

Yingying SunChunyan LiuTing JiaoNing XieHuaquan WangWeiwei QiZonghong Shao
Published in: International journal of hematology (2020)
The decreased expression of LAG3 on CD8+ Teffs, CD4+ Teffs and Tregs may be involved in the pathogenesis of SAA. LAG3 intervention may have therapeutic potential in treating SAA.
Keyphrases
  • regulatory t cells
  • poor prognosis
  • dendritic cells
  • induced apoptosis
  • randomized controlled trial
  • binding protein
  • cell cycle arrest
  • long non coding rna
  • nk cells
  • immune response
  • cell proliferation