RUNX3 Inhibits the Invasion and Metastasis of Human Colon Cancer HT-29 Cells by Upregulating MMP-2/9.

Jun Xue Xueliang Wu Ming Qu Fei Guo Lei Han Guangyuan Sun Zelong Yuan Shuang Fan Tian Li

Published in: Evidence-based complementary and alternative medicine : eCAM (2020)

RUNX3 can inhibit the invasion and metastasis of human colon cancer HT-29 cells, and the mechanism may be related to decreased expression of MMP-2 and MMP-9.

Keyphrases

cell migration
induced apoptosis
endothelial cells
cell cycle arrest
transcription factor
poor prognosis
induced pluripotent stem cells
pluripotent stem cells
endoplasmic reticulum stress
cell death
signaling pathway
binding protein