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SVExpress: identifying gene features altered recurrently in expression with nearby structural variant breakpoints.

Yiqun ZhangFengju ChenChad J Creighton
Published in: BMC bioinformatics (2021)
Our SVExpress tools allow computational biologists with a working knowledge of R to integrate gene expression with SV breakpoint data to identify recurrently altered genes. SVExpress is freely available for academic or commercial use at https://github.com/chadcreighton/SVExpress . SVExpress is implemented as a set of Excel macros and R code. All source code (R and Visual Basic for Applications) is available.
Keyphrases
  • gene expression
  • genome wide
  • genome wide identification
  • dna methylation
  • poor prognosis
  • healthcare
  • electronic health record
  • copy number
  • genome wide analysis
  • big data
  • bioinformatics analysis