Chad J Creighton (Chad Creighton, C J Creighton)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 71

Top Topics

Dna Methylation

Signaling Pathway

Top Venues

Nature communications

Cancer research communications

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Li Yang, Robert C Peery, Leah M Farmer, Xia Gao, Yiqun Zhang, Chad J Creighton, Lanjing Zhang, Lanlan Shen
Dietary Folate and Cofactors Accelerate Age-dependent p16 Epimutation to Promote Intestinal Tumorigenesis. Cancer research communications 4 (1) (2024)
Shouhui Yang, Wei Tang, Azadeh Azizian, Jochen Gaedcke, Yuuki Ohara, Helen Cawley, Nader Hanna, Michael Ghadimi, Trisha Lal, Subrata Sen, Chad J Creighton, Jianjun Gao, Nagireddy Putluri, Stefan Ambs, S Perwez Hussain
MIF/NR3C2 axis regulates glucose metabolism reprogramming in pancreatic cancer through MAPK-ERK and AP-1 pathways. Carcinogenesis 45 (8) (2024)
Chandra Sekhar Amara, Karthik Reddy Kami Reddy, Yang Yuntao, Yuen San Chan, Danthasinghe Waduge Badrajee Piyarathna, Lacey Elizabeth Dobrolecki, David J H Shih, Zhongcheng Shi, Jun Xu, Shixia Huang, Matthew J Ellis, Andrea B Apolo, Leomar Y Ballester, Jianjun Gao, Donna E Hansel, Yair Lotan, H Courtney Hodges, Seth P Lerner, Chad J Creighton, Arun Sreekumar, Wenjin Jim Zheng, Pavlos Msaouel, Shyam M Kavuri, Nagireddy Putluri
The IL6/JAK/STAT3 signaling axis is a therapeutic vulnerability in SMARCB1-deficient bladder cancer. Nature communications 15 (1) (2024)
Li Yang, Robert C Peery, Leah M Farmer, Xia Gao, Yiqun Zhang, Chad J Creighton, Lanjing Zhang, Lanlan Shen
Dietary Folate and Cofactors Accelerate Age-dependent p16 Epimutation to Promote Intestinal Tumorigenesis. Cancer research communications 4 (1) (2024)
Li Yang, Robert C Peery, Leah M Farmer, Xia Gao, Yiqun Zhang, Chad J Creighton, Lanjing Zhang, Lanlan Shen
Dietary Folate and Cofactors Accelerate Age-dependent p16 Epimutation to Promote Intestinal Tumorigenesis. Cancer research communications 4 (1) (2024)
Li Yang, Robert C Peery, Leah M Farmer, Xia Gao, Yiqun Zhang, Chad J Creighton, Lanjing Zhang, Lanlan Shen
Dietary Folate and Cofactors Accelerate Age-dependent p16 Epimutation to Promote Intestinal Tumorigenesis. Cancer research communications 4 (1) (2024)
Li Yang, Robert C Peery, Leah M Farmer, Xia Gao, Yiqun Zhang, Chad J Creighton, Lanjing Zhang, Lanlan Shen
Dietary Folate and Cofactors Accelerate Age-dependent p16 Epimutation to Promote Intestinal Tumorigenesis. Cancer research communications 4 (1) (2024)
Shouhui Yang, Wei Tang, Azadeh Azizian, Jochen Gaedcke, Yuuki Ohara, Helen Cawley, Nader Hanna, Michael Ghadimi, Trisha Lal, Subrata Sen, Chad J Creighton, Jianjun Gao, Nagireddy Putluri, Stefan Ambs, S Perwez Hussain
MIF/NR3C2 axis regulates glucose metabolism reprogramming in pancreatic cancer through MAPK-ERK and AP-1 pathways. Carcinogenesis 45 (8) (2024)
Li Yang, Robert C Peery, Leah M Farmer, Xia Gao, Yiqun Zhang, Chad J Creighton, Lanjing Zhang, Lanlan Shen
Dietary Folate and Cofactors Accelerate Age-dependent p16 Epimutation to Promote Intestinal Tumorigenesis. Cancer research communications 4 (1) (2024)
Li Yang, Robert C Peery, Leah M Farmer, Xia Gao, Yiqun Zhang, Chad J Creighton, Lanjing Zhang, Lanlan Shen
Dietary folate and cofactors accelerate age-dependent p16 epimutation to promote intestinal tumorigenesis. Cancer research communications (2024)
Shouhui Yang, Wei Tang, Azadeh Azizian, Jochen Gaedcke, Yuuki Ohara, Helen Cawley, Nader Hanna, Michael Ghadimi, Trisha Lal, Subrata Sen, Chad J Creighton, Jianjun Gao, Nagireddy Putluri, Stefan Ambs, S Perwez Hussain
MIF/NR3C2 axis regulates glucose metabolism reprogramming in pancreatic cancer through MAPK-ERK and AP-1 pathways. Carcinogenesis 45 (8) (2024)
Fengju Chen, Yiqun Zhang, Lanlan Shen, Chad J Creighton
The DNA methylome of pediatric brain tumors appears shaped by structural variation and predicts survival. Nature communications 15 (1) (2024)
Chandra Sekhar Amara, Karthik Reddy Kami Reddy, Yang Yuntao, Yuen San Chan, Danthasinghe Waduge Badrajee Piyarathna, Lacey Elizabeth Dobrolecki, David J H Shih, Zhongcheng Shi, Jun Xu, Shixia Huang, Matthew J Ellis, Andrea B Apolo, Leomar Y Ballester, Jianjun Gao, Donna E Hansel, Yair Lotan, H Courtney Hodges, Seth P Lerner, Chad J Creighton, Arun Sreekumar, Wenjin Jim Zheng, Pavlos Msaouel, Shyam M Kavuri, Nagireddy Putluri
The IL6/JAK/STAT3 signaling axis is a therapeutic vulnerability in SMARCB1-deficient bladder cancer. Nature communications 15 (1) (2024)
Li Yang, Robert C Peery, Leah M Farmer, Xia Gao, Yiqun Zhang, Chad J Creighton, Lanjing Zhang, Lanlan Shen
Dietary folate and cofactors accelerate age-dependent p16 epimutation to promote intestinal tumorigenesis. Cancer research communications (2024)
Fengju Chen, Yiqun Zhang, Lanlan Shen, Chad J Creighton
The DNA methylome of pediatric brain tumors appears shaped by structural variation and predicts survival. Nature communications 15 (1) (2024)
Fengju Chen, Yiqun Zhang, Lanlan Shen, Chad J Creighton
The DNA methylome of pediatric brain tumors appears shaped by structural variation and predicts survival. Nature communications 15 (1) (2024)
Li Yang, Robert C Peery, Leah M Farmer, Xia Gao, Yiqun Zhang, Chad J Creighton, Lanjing Zhang, Lanlan Shen
Dietary folate and cofactors accelerate age-dependent p16 epimutation to promote intestinal tumorigenesis. Cancer research communications (2024)
Chandra Sekhar Amara, Karthik Reddy Kami Reddy, Yang Yuntao, Yuen San Chan, Danthasinghe Waduge Badrajee Piyarathna, Lacey Elizabeth Dobrolecki, David J H Shih, Zhongcheng Shi, Jun Xu, Shixia Huang, Matthew J Ellis, Andrea B Apolo, Leomar Y Ballester, Jianjun Gao, Donna E Hansel, Yair Lotan, H Courtney Hodges, Seth P Lerner, Chad J Creighton, Arun Sreekumar, Wenjin Jim Zheng, Pavlos Msaouel, Shyam M Kavuri, Nagireddy Putluri
The IL6/JAK/STAT3 signaling axis is a therapeutic vulnerability in SMARCB1-deficient bladder cancer. Nature communications 15 (1) (2024)
Zhicheng Zhou, Deyong Jia, Ohjoon Kwon, Shan Li, Huiyun Sun, Martine P Roudier, Daniel W Lin, Lawrence True, Colm Morrissey, Chad J Creighton, John K Lee, Li Xin
Androgen-regulated stromal complement component 7 (C7) suppresses prostate cancer growth. Oncogene (2023)
Maya L Kriseman, Suni Tang, Zian Liao, Peixin Jiang, Sydney E Parks, Dominique I Cope, Fei Yuan, Fengju Chen, Ramya P Masand, Patricia D Castro, Michael M Ittmann, Chad J Creighton, Zhi Tan, Diana Monsivais
SMAD2/3 signaling in the uterine epithelium controls endometrial cell homeostasis and regeneration. Communications biology 6 (1) (2023)
Wen Bu, Chad J Creighton, Kelsey S Heavener, Carolina Gutierrez, Yongchao Dou, Amy T Ku, Yiqun Zhang, Weiyu Jiang, Jazmin Urrutia, Wen Jiang, Fei Yue, Luyu Jia, Ahmed Atef Ibrahim, Bing Zhang, Shixia Huang, Yi Li
Efficient cancer modeling through CRISPR-Cas9/HDR-based somatic precision gene editing in mice. Science advances 9 (19) (2023)
Wen Bu, Chad J Creighton, Kelsey S Heavener, Carolina Gutierrez, Yongchao Dou, Amy T Ku, Yiqun Zhang, Weiyu Jiang, Jazmin Urrutia, Wen Jiang, Fei Yue, Luyu Jia, Ahmed Atef Ibrahim, Bing Zhang, Shixia Huang, Yi Li
Efficient cancer modeling through CRISPR-Cas9/HDR-based somatic precision gene editing in mice. Science advances 9 (19) (2023)
Maya L Kriseman, Suni Tang, Zian Liao, Peixin Jiang, Sydney E Parks, Dominique I Cope, Fei Yuan, Fengju Chen, Ramya P Masand, Patricia D Castro, Michael M Ittmann, Chad J Creighton, Zhi Tan, Diana Monsivais
SMAD2/3 signaling in the uterine epithelium controls endometrial cell homeostasis and regeneration. Communications biology 6 (1) (2023)
Fengju Chen, Yiqun Zhang, Darshan S Chandrashekar, Sooryanarayana Varambally, Chad J Creighton
Global impact of somatic structural variation on the cancer proteome. Nature communications 14 (1) (2023)
Maya L Kriseman, Suni Tang, Zian Liao, Peixin Jiang, Sydney E Parks, Dominique I Cope, Fei Yuan, Fengju Chen, Ramya P Masand, Patricia D Castro, Michael M Ittmann, Chad J Creighton, Zhi Tan, Diana Monsivais
SMAD2/3 signaling in the uterine epithelium controls endometrial cell homeostasis and regeneration. Communications biology 6 (1) (2023)
Wen Bu, Chad J Creighton, Kelsey S Heavener, Carolina Gutierrez, Yongchao Dou, Amy T Ku, Yiqun Zhang, Weiyu Jiang, Jazmin Urrutia, Wen Jiang, Fei Yue, Luyu Jia, Ahmed Atef Ibrahim, Bing Zhang, Shixia Huang, Yi Li
Efficient cancer modeling through CRISPR-Cas9/HDR-based somatic precision gene editing in mice. Science advances 9 (19) (2023)
Maya L Kriseman, Suni Tang, Zian Liao, Peixin Jiang, Sydney E Parks, Dominique I Cope, Fei Yuan, Fengju Chen, Ramya P Masand, Patricia D Castro, Michael M Ittmann, Chad J Creighton, Zhi Tan, Diana Monsivais
SMAD2/3 signaling in the uterine epithelium controls endometrial cell homeostasis and regeneration. Communications biology 6 (1) (2023)
Wen Bu, Chad J Creighton, Kelsey S Heavener, Carolina Gutierrez, Yongchao Dou, Amy T Ku, Yiqun Zhang, Weiyu Jiang, Jazmin Urrutia, Wen Jiang, Fei Yue, Luyu Jia, Ahmed Atef Ibrahim, Bing Zhang, Shixia Huang, Yi Li
Efficient cancer modeling through CRISPR-Cas9/HDR-based somatic precision gene editing in mice. Science advances 9 (19) (2023)
Pavan Reddy, Dongchang Zhao, Visweswaran Ravikumar, Emma Lauder, Lu Li, Yaping Sun, Katherine Oravecz-Wilson, Michael Brooks, Evan T Keller, Fengju Chen, Laure Maneix, Ana Santibanez, Chad J Creighton, Arvind Rao
Inflammatory memory restrains intestinal stem cell regeneration. Research square (2023)
Maya L Kriseman, Suni Tang, Zian Liao, Peixin Jiang, Sydney E Parks, Dominique I Cope, Fei Yuan, Fengju Chen, Ramya P Masand, Patricia D Castro, Michael M Ittmann, Chad J Creighton, Zhi Tan, Diana Monsivais
SMAD2/3 signaling in the uterine epithelium controls endometrial cell homeostasis and regeneration. Communications biology 6 (1) (2023)
Yuan Yuan, Young Seok Ju, Young-Wook Kim, Jun Li, Yumeng Wang, Christopher J Yoon, Yang Yang, Inigo Martincorena, Chad J Creighton, John N Weinstein, Yanxun Xu, Leng Han, Hyung-Lae Kim, Hidewaki Nakagawa, Keunchil Park, Peter J Campbell, Han Liang, null null
Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers. Nature genetics (2023)
Maya L Kriseman, Suni Tang, Zian Liao, Peixin Jiang, Sydney E Parks, Dominique I Cope, Fei Yuan, Fengju Chen, Ramya P Masand, Patricia D Castro, Michael M Ittmann, Chad J Creighton, Zhi Tan, Diana Monsivais
SMAD2/3 signaling in the uterine epithelium controls endometrial cell homeostasis and regeneration. Communications biology 6 (1) (2023)
Jun Li, Hengyu Lu, Patrick Kwok-Shing Ng, Angeliki Pantazi, Carman Ka Man Ip, Kang Jin Jeong, Bianca Amador, Richard Tran, Yiu Huen Tsang, Lixing Yang, Xingzhi Song, Turgut Dogruluk, Xiaojia Ren, Angela Hadjipanayis, Christopher A Bristow, Semin Lee, Melanie Kucherlapati, Michael Parfenov, Jiabin Tang, Sahil B Seth, Harshad S Mahadeshwar, Kamalika Mojumdar, Dong Zeng, Jianhua Zhang, Alexei Protopopov, Jonathan G Seidman, Chad J Creighton, Yiling Lu, Nidhi Sahni, Kenna R Shaw, Funda Meric-Bernstam, P Andrew Futreal, Lynda Chin, Kenneth L Scott, Raju Kucherlapati, Gordon B Mills, Han Liang
A functional genomic approach to actionable gene fusions for precision oncology. Science advances 8 (6) (2022)
Susana Garcia-Recio, Toshinori Hinoue, Gregory L Wheeler, Benjamin J Kelly, Ana Christina Garrido-Castro, Tomas Pascual, Aguirre A De Cubas, Youli Xia, Brooke M Felsheim, Marni B McClure, Andrei Rajkovic, Ezgi Karaesmen, Markia A Smith, Cheng Fan, Paula I Gonzalez Ericsson, Melinda E Sanders, Chad J Creighton, Jay Bowen, Kristen Leraas, Robyn T Burns, Sara Coppens, Amy Wheless, Salma Rezk, Amy L Garrett, Joel S Parker, Kelly K Foy, Hui Shen, Ben H Park, Ian Krop, Carey K Anders, Julie Gastier-Foster, Mothaffar F Rimawi, Rita Nanda, Nancy U Lin, Claudine Isaacs, P Kelly Marcom, Anna Maria Storniolo, Fergus J Couch, Uma Chandran, Michael Davis, Jonathan C Silverstein, Alexander J Ropelewski, Minetta C Liu, Susan G Hilsenbeck, Larry Norton, Andrea L Richardson, William Fraser Symmans, Antonio C Wolff, Nancy E Davidson, Lisa Anne Carey, Adrian V Lee, Justin M Balko, Katherine A Hoadley, Peter W Laird, Elaine R Mardis, Tari A King, null null, Charles M Perou
Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis. Nature cancer 4 (1) (2022)
Wei Wang, Dong Han, Qinbo Cai, Tao Shen, Bingning Dong, Michael T Lewis, Runsheng Wang, Yanling Meng, Wolong Zhou, Ping Yi, Chad J Creighton, David D Moore, Feng Yang
MAPK4 promotes triple negative breast cancer growth and reduces tumor sensitivity to PI3K blockade. Nature communications 13 (1) (2022)
Susana Garcia-Recio, Toshinori Hinoue, Gregory L Wheeler, Benjamin J Kelly, Ana Christina Garrido-Castro, Tomas Pascual, Aguirre A De Cubas, Youli Xia, Brooke M Felsheim, Marni B McClure, Andrei Rajkovic, Ezgi Karaesmen, Markia A Smith, Cheng Fan, Paula I Gonzalez Ericsson, Melinda E Sanders, Chad J Creighton, Jay Bowen, Kristen Leraas, Robyn T Burns, Sara Coppens, Amy Wheless, Salma Rezk, Amy L Garrett, Joel S Parker, Kelly K Foy, Hui Shen, Ben H Park, Ian Krop, Carey K Anders, Julie Gastier-Foster, Mothaffar F Rimawi, Rita Nanda, Nancy U Lin, Claudine Isaacs, P Kelly Marcom, Anna Maria Storniolo, Fergus J Couch, Uma Chandran, Michael Davis, Jonathan C Silverstein, Alexander J Ropelewski, Minetta C Liu, Susan G Hilsenbeck, Larry Norton, Andrea L Richardson, William Fraser Symmans, Antonio C Wolff, Nancy E Davidson, Lisa Anne Carey, Adrian V Lee, Justin M Balko, Katherine A Hoadley, Peter W Laird, Elaine R Mardis, Tari A King, null null, Charles M Perou
Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis. Nature cancer 4 (1) (2022)
Susana Garcia-Recio, Toshinori Hinoue, Gregory L Wheeler, Benjamin J Kelly, Ana Christina Garrido-Castro, Tomas Pascual, Aguirre A De Cubas, Youli Xia, Brooke M Felsheim, Marni B McClure, Andrei Rajkovic, Ezgi Karaesmen, Markia A Smith, Cheng Fan, Paula I Gonzalez Ericsson, Melinda E Sanders, Chad J Creighton, Jay Bowen, Kristen Leraas, Robyn T Burns, Sara Coppens, Amy Wheless, Salma Rezk, Amy L Garrett, Joel S Parker, Kelly K Foy, Hui Shen, Ben H Park, Ian Krop, Carey K Anders, Julie Gastier-Foster, Mothaffar F Rimawi, Rita Nanda, Nancy U Lin, Claudine Isaacs, P Kelly Marcom, Anna Maria Storniolo, Fergus J Couch, Uma Chandran, Michael Davis, Jonathan C Silverstein, Alexander J Ropelewski, Minetta C Liu, Susan G Hilsenbeck, Larry Norton, Andrea L Richardson, William Fraser Symmans, Antonio C Wolff, Nancy E Davidson, Lisa Anne Carey, Adrian V Lee, Justin M Balko, Katherine A Hoadley, Peter W Laird, Elaine R Mardis, Tari A King, null null, Charles M Perou
Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis. Nature cancer 4 (1) (2022)
Meng Lin, Amy T Ku, Jie Dong, Fei Yue, Weiyu Jiang, Ahmed Atef Ibrahim, Fanglue Peng, Chad J Creighton, Chandandeep Nagi, Carolina Gutierrez, Jeffrey M Rosen, Xiang H F Zhang, Susan G Hilsenbeck, Xi Chen, Yi-Chieh Nancy Du, Shixia Huang, Aiping Shi, Zhimin Fan, Yi Li
STAT5 confers lactogenic properties in breast tumorigenesis and restricts metastatic potential. Oncogene 41 (48) (2022)
Susana Garcia-Recio, Toshinori Hinoue, Gregory L Wheeler, Benjamin J Kelly, Ana Christina Garrido-Castro, Tomas Pascual, Aguirre A De Cubas, Youli Xia, Brooke M Felsheim, Marni B McClure, Andrei Rajkovic, Ezgi Karaesmen, Markia A Smith, Cheng Fan, Paula I Gonzalez Ericsson, Melinda E Sanders, Chad J Creighton, Jay Bowen, Kristen Leraas, Robyn T Burns, Sara Coppens, Amy Wheless, Salma Rezk, Amy L Garrett, Joel S Parker, Kelly K Foy, Hui Shen, Ben H Park, Ian Krop, Carey K Anders, Julie Gastier-Foster, Mothaffar F Rimawi, Rita Nanda, Nancy U Lin, Claudine Isaacs, P Kelly Marcom, Anna Maria Storniolo, Fergus J Couch, Uma Chandran, Michael Davis, Jonathan C Silverstein, Alexander J Ropelewski, Minetta C Liu, Susan G Hilsenbeck, Larry Norton, Andrea L Richardson, William Fraser Symmans, Antonio C Wolff, Nancy E Davidson, Lisa Anne Carey, Adrian V Lee, Justin M Balko, Katherine A Hoadley, Peter W Laird, Elaine R Mardis, Tari A King, null null, Charles M Perou
Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis. Nature cancer (2022)
Yiqun Zhang, Fengju Chen, Darshan S Chandrashekar, Sooryanarayana Varambally, Chad J Creighton
Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways. Nature communications 13 (1) (2022)
Susana Garcia-Recio, Toshinori Hinoue, Gregory L Wheeler, Benjamin J Kelly, Ana Christina Garrido-Castro, Tomas Pascual, Aguirre A De Cubas, Youli Xia, Brooke M Felsheim, Marni B McClure, Andrei Rajkovic, Ezgi Karaesmen, Markia A Smith, Cheng Fan, Paula I Gonzalez Ericsson, Melinda E Sanders, Chad J Creighton, Jay Bowen, Kristen Leraas, Robyn T Burns, Sara Coppens, Amy Wheless, Salma Rezk, Amy L Garrett, Joel S Parker, Kelly K Foy, Hui Shen, Ben H Park, Ian Krop, Carey K Anders, Julie Gastier-Foster, Mothaffar F Rimawi, Rita Nanda, Nancy U Lin, Claudine Isaacs, P Kelly Marcom, Anna Maria Storniolo, Fergus J Couch, Uma Chandran, Michael Davis, Jonathan C Silverstein, Alexander J Ropelewski, Minetta C Liu, Susan G Hilsenbeck, Larry Norton, Andrea L Richardson, William Fraser Symmans, Antonio C Wolff, Nancy E Davidson, Lisa Anne Carey, Adrian V Lee, Justin M Balko, Katherine A Hoadley, Peter W Laird, Elaine R Mardis, Tari A King, null null, Charles M Perou
Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis. Nature cancer 4 (1) (2022)
Oh-Joon Kwon, Boyu Zhang, Deyong Jia, Li Zhang, Xing Wei, Zhicheng Zhou, Deli Liu, Khoi Trung Huynh, Kai Zhang, Yiqun Zhang, Paul Labhart, Andrea Sboner, Chris Barbieri, Michael C Haffner, Chad J Creighton, Li Xin
Elevated expression of the colony-stimulating factor 1 (CSF1) induces prostatic intraepithelial neoplasia dependent of epithelial-Gp130. Oncogene 41 (9) (2022)
Yiqun Zhang, Fengju Chen, Nuno A Fonseca, Yao He, Masashi Fujita, Hidewaki Nakagawa, Zemin Zhang, Alvis Brazma, null null, null null, Chad J Creighton, null null
Author Correction: High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations. Nature communications 13 (1) (2022)
Yiqun Zhang, Fengju Chen, Darshan S Chandrashekar, Sooryanarayana Varambally, Chad J Creighton
Author Correction: Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways. Nature communications 13 (1) (2022)
Xiaochao Tan, Priyam Banerjee, Edward A Pham, Florentine U N Rutaganira, Kaustabh Basu, Neus Bota-Rabassedas, Hou-Fu Guo, Caitlin L Grzeskowiak, Xin Liu, Jiang Yu, Lei Shi, David H Peng, B Leticia Rodriguez, Jiaqi Zhang, Veronica Zheng, Dzifa Y Duose, Luisa Maren Solis Soto, Barbara Mino, Maria Gabriela Raso, Carmen Behrens, Ignacio I Wistuba, Kenneth L Scott, Mark Smith, Khanh Nguyen, Grace Lam, Ingrid Choong, Abhijit Mazumdar, Jamal L Hill, Don L Gibbons, Powel H Brown, William K Russell, Kevan M Shokat, Chad J Creighton, Jeffrey S Glenn
PI4KIIIβ is a therapeutic target in chromosome 1q-amplified lung adenocarcinoma. Science translational medicine 12 (527) (2021)
Hou-Fu Guo, Maria Neus Bota Rabassedas, Masahiko Terajima, B Leticia Rodriguez, Don L Gibbons, Yulong Chen, Priyam Banerjee, Chi-Lin Tsai, Xiaochao Tan, Xin Liu, Jiang Yu, Michal Tokmina-Roszyk, Roma Stawikowska, Gregg B Fields, Mitchell D Miller, Xiaoyan Wang, Juhoon Lee, Kevin N Dalby, Chad J Creighton, George N Philips, John A Tainer, Mitsuo Yamauchi, Jonathan M Kurie
A collagen glucosyltransferase drives lung adenocarcinoma progression in mice. Communications biology 4 (1) (2021)
Priyam Banerjee, Guan-Yu Xiao, Xiaochao Tan, Veronica J Zheng, Lei Shi, Maria Neus Bota Rabassedas, Hou-Fu Guo, Xin Liu, Jiang Yu, Lixia Diao, Jing Wang, William K Russell, Jason Roszik, Chad J Creighton, Jonathan M Kurie
The EMT activator ZEB1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells. Nature communications 12 (1) (2021)
Yiqun Zhang, Fengju Chen, Chad J Creighton
SVExpress: identifying gene features altered recurrently in expression with nearby structural variant breakpoints. BMC bioinformatics 22 (1) (2021)
Qinbo Cai, Chunfang Zhang, Wei Wang, Bingning Dong, Dong Han, Tao Shen, Chad J Creighton, David D Moore, Feng Yang
MAPK6-AKT signaling promotes tumor growth and resistance to mTOR kinase blockade. Science advances 7 (46) (2021)
Diana Monsivais, Takashi Nagashima, Renata Prunskaite-Hyyryläinen, Kaori Nozawa, Keisuke Shimada, Suni Tang, Clark Hamor, Julio E Agno, Fengju Chen, Ramya P Masand, Steven L Young, Chad J Creighton, Francesco J DeMayo, Masahito Ikawa, Se-Jin Lee, Martin M Matzuk
Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis. Nature communications 12 (1) (2021)
Fengju Chen, Yiqun Zhang, Chad J Creighton
Systematic identification of non-coding somatic single nucleotide variants associated with altered transcription and DNA methylation in adult and pediatric cancers. NAR cancer 3 (1) (2021)
Diana Monsivais, Yasmin M Vasquez, Fengju Chen, Yiqun Zhang, Darshan S Chandrashekar, John C Faver, Ramya P Masand, Michael E Scheurer, Sooryanarayana Varambally, Martin M Matzuk, Chad J Creighton
Mass-spectrometry-based proteomic correlates of grade and stage reveal pathways and kinases associated with aggressive human cancers. Oncogene 40 (11) (2021)
Xiaochao Tan, Priyam Banerjee, Lei Shi, Guan-Yu Xiao, B Leticia Rodriguez, Caitlin L Grzeskowiak, Xin Liu, Jiang Yu, Don L Gibbons, William K Russell, Chad J Creighton
p53 loss activates prometastatic secretory vesicle biogenesis in the Golgi. Science advances 7 (25) (2021)
Hsiu-Chi Lee, Chien-Hui Ou, Yun-Chen Huang, Pei-Chi Hou, Chad J Creighton, Yi-Syuan Lin, Che-Yuan Hu, Shih-Chieh Lin
YAP1 overexpression contributes to the development of enzalutamide resistance by induction of cancer stemness and lipid metabolism in prostate cancer. Oncogene 40 (13) (2021)
Yiqun Zhang, Fengju Chen, Lawrence A Donehower, Michael E Scheurer, Chad J Creighton
A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement. Nature communications 12 (1) (2021)
Yuan Yuan, Young Seok Ju, Young-Wook Kim, Jun Li, Yumeng Wang, Christopher J Yoon, Yang Yang, Inigo Martincorena, Chad J Creighton, John N Weinstein, Yanxun Xu, Leng Han, Hyung-Lae Kim, Hidewaki Nakagawa, Keunchil Park, Peter J Campbell, Han Liang, null null
Publisher Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers. Nature genetics (2020)
Jody Vykoukal, Johannes F Fahrmann, Justin R Gregg, Zhe Tang, Spyridon Basourakos, Ehsan Irajizad, Sanghee Park, Guang Yang, Chad J Creighton, Alia Fleury, Jeffrey Mayo, Adriana Paulucci-Holthauzen, Jennifer B Dennison, Eunice Murage, Christine B Peterson, John W Davis, Jeri Kim, Samir M Hanash, Timothy C Thompson
Caveolin-1-mediated sphingolipid oncometabolism underlies a metabolic vulnerability of prostate cancer. Nature communications 11 (1) (2020)
Chad J Creighton
Proteomic signatures of clear cell renal cell carcinoma. Nature reviews. Nephrology 16 (3) (2020)
Xiyin Wang, Jillian R H Wendel, Robert E Emerson, Russell R Broaddus, Chad J Creighton, Douglas B Rusch, Aaron Buechlein, Francesco J DeMayo, John P Lydon, Shannon M Hawkins
Pten and Dicer1 loss in the mouse uterus causes poorly differentiated endometrial adenocarcinoma. Oncogene 39 (40) (2020)
Rakhee Bajaj, Samrat T Kundu, Caitlin L Grzeskowiak, Jared F Fradette, Kenneth L Scott, Chad J Creighton, Don L Gibbons
IMPAD1 and KDELR2 drive invasion and metastasis by enhancing Golgi-mediated secretion. Oncogene 39 (37) (2020)
Yiqun Zhang, Fengju Chen, Nuno A Fonseca, Yao He, Masashi Fujita, Hidewaki Nakagawa, Zemin Zhang, Alvis Brazma, null null, null null, Chad J Creighton, null null
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations. Nature communications 11 (1) (2020)
Yuan Yuan, Young Seok Ju, Young-Wook Kim, Jun Li, Yumeng Wang, Christopher J Yoon, Yang Yang, Inigo Martincorena, Chad J Creighton, John N Weinstein, Yanxun Xu, Leng Han, Hyung-Lae Kim, Hidewaki Nakagawa, Keunchil Park, Peter J Campbell, Han Liang, null null
Comprehensive molecular characterization of mitochondrial genomes in human cancers. Nature genetics 52 (3) (2020)
Margeaux Wetendorf, Rong Li, San Pin Wu, Jian Liu, Chad J Creighton, Tianyuan Wang, Kyathanahalli S Janardhan, Cynthia J Willson, Rainer B Lanz, Bruce D Murphy, John P Lydon, Francesco J DeMayo
Constitutive expression of progesterone receptor isoforms promotes the development of hormone-dependent ovarian neoplasms. Science signaling 13 (652) (2020)
Olga Kim, Eun Young Park, David L Klinkebiel, Svetlana D Pack, Yong-Hyun Shin, Zied Abdullaev, Robert E Emerson, Donna M Coffey, Sun Young Kwon, Chad J Creighton, Sanghoon Kwon, Edmund C Chang, Theodore Chiang, Alexander N Yatsenko, Jeremey Chien, Dong-Joo Cheon, Yang Yang-Hartwich, Harikrishna Nakshatri, Kenneth P Nephew, Richard R Behringer, Facundo M Fernández, Chi Heum Cho, Barbara C Vanderhyden, Ronny Drapkin, Robert C Bast, Kathy D Miller, Adam R Karpf, Jaeyeon Kim
In vivo modeling of metastatic human high-grade serous ovarian cancer in mice. PLoS genetics 16 (6) (2020)
Yuan Yuan, Young Seok Ju, Young-Wook Kim, Jun Li, Yumeng Wang, Christopher J Yoon, Yang Yang, Inigo Martincorena, Chad J Creighton, John N Weinstein, Yanxun Xu, Leng Han, Hyung-Lae Kim, Hidewaki Nakagawa, Keunchil Park, Peter J Campbell, Han Liang, null null
Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers. Nature genetics (2020)
S J Kim, S Garcia-Recio, Chad J Creighton, Charles M Perou, Jeffrey M Rosen
Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression. Oncogene 38 (31) (2019)
Fengju Chen, Darshan S Chandrashekar, Sooryanarayana Varambally, Chad J Creighton
Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers. Nature communications 10 (1) (2019)
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