Correlation between ELF-PEMF exposure and Human RPE Cell Proliferation, Apoptosis and Gene Expression.
Morteza OladnabiMohammad Amir MishanMozhgan RezaeikanaviMehryar ZargariRouhallah Najjar SadeghiAbouzar BagheriPublished in: Journal of ophthalmic & vision research (2021)
As ELF-PEMF showed inhibitory effects on the expression of angiogenic genes in hRPE cells with no cytotoxic or proliferative side effects, it can be introduced as a useful procedure for managing angiogenesis induced by retinal pathogenesis, although more studies with adequate follow-up in animal models are needed.
Keyphrases
- cell cycle arrest
- endothelial cells
- gene expression
- cell proliferation
- pi k akt
- induced apoptosis
- cell death
- endoplasmic reticulum stress
- poor prognosis
- oxidative stress
- dna methylation
- diabetic retinopathy
- optical coherence tomography
- genome wide
- cell cycle
- vascular endothelial growth factor
- induced pluripotent stem cells
- pluripotent stem cells
- case control
- optic nerve
- wound healing
- long non coding rna
- genome wide analysis