Nuclear nonmetastatic protein 23-H1 expression and epithelial-mesenchymal transition in laryngeal carcinoma: A pilot investigation.

Gino Marioni Rocco CappellessoGiancarlo OttavianoElena FasanaroRosario Marchese-RagonaNiccolò FavarettoLuciano GiacomelliVincenza GuzzardoAlessandro MartiniAmbrogio FassinaStella Blandamura

Published in: Head & neck (2018)

Nuclear nm23-H1 expression warrants further investigation in laryngeal SCC as a prognostic marker identifying patients at higher risk of recurrence. nm23-H1 targeted treatments may be capable of regulating epithelial-to-mesenchymal transition.

Keyphrases

epithelial mesenchymal transition
poor prognosis
binding protein
photodynamic therapy
long non coding rna
transforming growth factor
signaling pathway
cancer therapy
randomized controlled trial
free survival
small molecule