Scale and Scope of Gene-Alcohol Interactions in Chronic Pancreatitis: A Systematic Review.

Jian-Min Chen Anthony Francis Herzig French Exome ConsortiumEmmanuelle MassonDavid N CooperClaude Férec

Published in: Genes (2021)

This study revealed evidence for extensive gene-alcohol interactions in CP. Our findings lend support to the hypothesis that alcohol affects the expression of genetically determined CP and highlight a predominant role of weak-effect variants in the development of ACP.

Keyphrases

copy number
alcohol consumption
genome wide
poor prognosis
genome wide identification
single cell
dna methylation
long non coding rna
binding protein
genome wide analysis