Salivary microRNA-126 and 135a: a potentially non-invasive diagnostic biomarkers of type- 2 diabetes.
Yousef Khazaei MonfaredMohammad-Reza Mirzaii-DizgahElham KhodabandehlooMohamad Reza SarookhaniSima HashemipourIraj Mirzaii-DizgahPublished in: Journal of diabetes and metabolic disorders (2021)
The results of this case and control study showed that miR-135a and miR126 expression in saliva fluid as a reliable biomarkers and non-invasive approach in combination by change of lipid profiles, glucose and HbA1c may be used to monitor diabetic and non-diabetic patients, while further research is needed to investigate the relationship of these salivary miRNAs (miR135a, miR126) levels change on shifting the levels of clinical laboratory outcomes.