The Blood and Muscle Expression Pattern of the Equine TCAP Gene during the Race Track Training of Arabian Horses.
Monika StefaniukTomasz SzmatołaJoanna ŁątkaBogusława DługoszKatarzyna Ropka-MolikPublished in: Animals : an open access journal from MDPI (2019)
Horse musculature has been shaped through evolution by environmental and human factors, which has resulted in several extraordinary adaptations to physical effort. Skeletal muscle plasticity results from the response to mechanical stimulation causing hypertrophy, where sarcomeres increase the muscle's cross-sectional area under the influence of contractile forces. The aim of the present study was the evaluation of transcript abundance of the telethonin (TCAP) gene, which is a part of the sarcomere macromolecular mechanosensory complex in the gluteus medius muscle, and the whole blood of Arabian horses during flat race training. The analysis, performed by quantitative PCR, showed an increase of TCAP transcripts in skeletal muscle. However, in whole blood, the transcript abundance decreased after the first stage of training and further increased after the second phase. The obtained results indicate a lack of similarity of TCAP gene expression in both tissues.
Keyphrases
- skeletal muscle
- gene expression
- insulin resistance
- cross sectional
- virtual reality
- copy number
- endothelial cells
- genome wide
- poor prognosis
- dna methylation
- physical activity
- antibiotic resistance genes
- high resolution
- mental health
- genome wide identification
- risk assessment
- climate change
- human health
- genome wide analysis
- adipose tissue
- binding protein
- induced pluripotent stem cells
- single cell
- metabolic syndrome