Login / Signup
IL2RG-deficient minipigs generated via CRISPR/Cas9 technology support the growth of human melanoma-derived tumours.
Jilong Ren
Dawei Yu
Rui Fu
Peipei An
Renren Sun
Zhengzhu Wang
Runfa Guo
Haoyun Li
Ying Zhang
Ziyi Li
Yong-Guang Yang
Wei Li
Tang Hai
Zheng Hu
Published in:
Cell proliferation (2020)
Our results indicate that these pigs are promising hosts for modelling human cancer in vivo, which may aid in the discovery and development of anti-cancer drugs.
Keyphrases
</>
endothelial cells
crispr cas
induced pluripotent stem cells
pluripotent stem cells
genome editing
small molecule
papillary thyroid
high throughput
squamous cell
young adults
lymph node metastasis
drug induced
skin cancer