Ligand-activated PPARδ expression promotes hepatocellular carcinoma progression by regulating the PI3K-AKT signaling pathway.

Wei HanNan WangRui KongWen BaoWei Han

Published in: Journal of translational medicine (2022)

PPARδ plays an important part in HCC progression, penetrating investigation of the related regulatory mechanism may shed light upon further biological and pharmacological value.

Keyphrases

signaling pathway
poor prognosis
insulin resistance
transcription factor
pi k akt
fatty acid
binding protein
type diabetes
adipose tissue
oxidative stress
metabolic syndrome
induced apoptosis
skeletal muscle
cell proliferation