Type 2 diabetes mellitus accelerates brain aging and cognitive decline: Complementary findings from UK Biobank and meta-analyses.
Botond B AntalLiam P McMahonSyed Fahad SultanAndrew LithenDeborah J WexlerBradford DickersonEva-Maria RataiLilianne Rivka Mujica-ParodiPublished in: eLife (2022)
The research described in this article was funded by the W. M. Keck Foundation (to LRMP), the White House Brain Research Through Advancing Innovative Technologies (BRAIN) Initiative (NSFNCS-FR 1926781 to LRMP), and the Baszucki Brain Research Fund (to LRMP). None of the funding sources played any role in the design of the experiments, data collection, analysis, interpretation of the results, the decision to publish, or any aspect relevant to the study. DJW reports serving on data monitoring committees for Novo Nordisk. None of the authors received funding or in-kind support from pharmaceutical and/or other companies to write this article.
Keyphrases
- cognitive decline
- resting state
- white matter
- functional connectivity
- systematic review
- meta analyses
- cerebral ischemia
- mild cognitive impairment
- electronic health record
- randomized controlled trial
- type diabetes
- big data
- drinking water
- metabolic syndrome
- machine learning
- cross sectional
- brain injury
- weight loss
- blood brain barrier
- drug induced