Partial Restoration of Brain Dystrophin and Behavioral Deficits by Exon Skipping in the Muscular Dystrophy X-Linked (mdx) Mouse.

Faouzi ZarroukiKarima RelizaniFlavien BizotThomas TensorerLuis GarciaCyrille VaillendAurelie T Goyenvalle

Published in: Annals of neurology (2022)

These results suggest for the first time that postnatal re-expression of brain dystrophin could reverse or at least alleviate some cognitive deficits associated with Duchenne muscular dystrophy. ANN NEUROL 2022;92:213-229.

Keyphrases

duchenne muscular dystrophy
muscular dystrophy
resting state
white matter
poor prognosis
functional connectivity
traumatic brain injury
cerebral ischemia
preterm infants
binding protein
neural network
blood brain barrier
subarachnoid hemorrhage