HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor.
Matthew L HemmingShannon CoyJia-Ren LinJessica L AndersenJoanna PrzybylEmanuele MazzolaAmr H Abdelhamid AhmedMatt van de RijnPeter Karl SorgerScott A ArmstrongGeorge D DemetriSandro SantagataPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Our results define anatomic and transcriptional determinants of GIST and molecular origins of clinical phenotypes. Assessment of HAND1 and BARX1 expression in GIST may provide prognostic information and improve clinical decisions on the administration of adjuvant therapy.