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Effects of low-dose chlorpyrifos on neurobehavior and potential mechanisms: A review of studies in rodents, zebrafish, and Caenorhabditis elegans.

Marilyn H Silva
Published in: Birth defects research (2020)
Taken together, these findings provided a weight-of-evidence for low-dose CPF neurotoxicity and noncholinergic mechanisms. Variability in laboratories, exposure methods, tests, sex, and animal species/strain might have contributed to the inconsistent results. The detrimental CPF effects during early development are relevant to human populations.
Keyphrases
  • low dose
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  • body mass index
  • induced pluripotent stem cells
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  • pluripotent stem cells
  • risk assessment
  • human health