Immunomodulatory effects of probiotic supplementation in patients with asthma: a randomized, double-blind, placebo-controlled trial.
Sina SadrifarTannaz Abbasi-DokhtSarvenaz ForouzandehFarhad MalekBahman YousefiAmir Salek FarrokhiJafar KaramiRasoul BaharlouPublished in: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology (2023)
In our study, 8-week treatment with probiotic supplementation led to reduced Th2 cells-associated IL-4 and improved Forced Expiratory Volume and Forced Vital Capacity. It appears probiotics can be used in addition to common asthma treatments.
Keyphrases
- double blind
- chronic obstructive pulmonary disease
- placebo controlled
- lung function
- induced apoptosis
- allergic rhinitis
- clinical trial
- study protocol
- bacillus subtilis
- cell cycle arrest
- cystic fibrosis
- randomized controlled trial
- mechanical ventilation
- air pollution
- endoplasmic reticulum stress
- phase ii
- lactic acid
- cell death
- signaling pathway
- replacement therapy