Single-cell transcriptomic analysis deciphers key transitional signatures associated with oncogenic evolution in human intramucosal oesophageal squamous cell carcinoma.

Xin-Yang LiuYan-Bo LiuJia-Cheng XuYi-Fei ZhangYuan-Yuan RuanYi ZhaoLin-Feng WuJian-Wei HuZhen ZhangMeng-Jiang HeTian-Yin ChenXiao-Yue XuJing-Wei ZhangYi-Qun Zhang Ping Hong Zhou

Published in: Clinical and translational medicine (2023)

This study demonstrates the changes of cell subsets and transcriptional levels in human intramucosal ESCC, which may provide unique insights into the development of novel biomarkers and potential intervention strategies.

Keyphrases

single cell
endothelial cells
squamous cell carcinoma
randomized controlled trial
transcription factor
induced pluripotent stem cells
rna seq
pluripotent stem cells
gene expression
stem cells
high throughput
genome wide
mesenchymal stem cells
oxidative stress
heat stress
heat shock protein