Neonatal adiposity is associated with microRNAs in adipocyte-derived extracellular vesicles in maternal and cord blood, a discovery analysis.

Pooja KunteMatthew BarberioPradeep TiwariKrishna SuklaBrennan HarmonSamuel EpsteinDattatray BhatKayla AutheletMadeleine GoldbergSudha RaoHemant DamleRobert J FreishtatChittaranjan S Yajnik

Published in: International journal of obesity (2005) (2023)

Our results suggest that the ADsEV miRNAs in mothers are potential regulators of fetal adiposity. The expression and functionality of miRNAs appear to be influenced by maternal adiposity, hyperglycemia, and micronutrient status during pregnancy.

Keyphrases

insulin resistance
cord blood
birth weight
weight gain
adipose tissue
poor prognosis
pregnancy outcomes
skeletal muscle
small molecule
transcription factor
high throughput
fatty acid
binding protein
oxidative stress