Liver X Receptor Exerts Anti-Inflammatory Effects in Colonic Epithelial Cells via ABCA1 and Its Expression Is Decreased in Human and Experimental Inflammatory Bowel Disease.

José Miranda-BautistaJuan A Rodríguez-FeoMarta PuertoBeatriz López-CauceJosé M LaraRaquel González-NovoDavid Martín-HernándezRocío Ferreiro-IglesiasRafael BañaresLuis A Menchen

Published in: Inflammatory bowel diseases (2022)

The LXR-ABCA1 pathway exerts anti-inflammatory effects in intestinal epithelial cells and is impaired in the colonic mucosa of patients with IBD and IL-10-/- mice.

Keyphrases

ulcerative colitis
endothelial cells
poor prognosis
binding protein
induced pluripotent stem cells
high fat diet induced
pluripotent stem cells
metabolic syndrome
adipose tissue
wild type
insulin resistance