Associations between obesity-related gene expression in maternal and cord blood and newborn adiposity: findings from the Araraquara Cohort study.
P NakandakareC F NicolettiN Y NoronhaC B NoninoP P ArgentatoN N DejaniL A LuziaM M RogeroPatrícia Helen de Carvalho RondóPublished in: International journal of obesity (2005) (2021)
To our knowledge, this is the first study to evaluate the relationship of maternal and cord blood gene expression with adiposity markers of the newborn. Our results provide evidence for the contribution of maternal and cord blood gene expression-particularly maternal PPARG and TLR4 expression, and cord blood IL-10 expression-to newborn weight, BMI, and fat mass %.
Keyphrases
- cord blood
- gene expression
- birth weight
- weight gain
- dna methylation
- insulin resistance
- poor prognosis
- pregnancy outcomes
- body mass index
- weight loss
- metabolic syndrome
- healthcare
- adipose tissue
- type diabetes
- physical activity
- inflammatory response
- immune response
- binding protein
- skeletal muscle
- fatty acid
- gestational age
- pregnant women