Evaluation of Botox treatment in patients with chronic scrotal pain: Protocol for a randomized double-blinded control trial.
Nicolai Skov SchiellerupHanne KobberøKarin AndersenCharlotte Aaberg PoulsenMads Hvid PoulsenPublished in: BJUI compass (2024)
The study will include 50 patients for randomization to either spermatic cord block with 100 IE BTX or sterile saline. All patients will prior to randomization undergo physical examination and will be asked to fulfil multiple questionnaires regarding pain and impact in daily life, that is, (1) visual analogue score for pain, (2) quality of life (EQ-5D-5L), (3) Chronic Prostatitis Symptom Index (NIH-CPSI), (4) ICD-10 depression questionnaire (MDI), (5) Likert global assessment scale, and (6) International Index of Erectile Function questionnaire. Physical examination and fulfilment of the questionnaires will be repeated multiple times throughout the study period of 12 weeks. After this time point, patients will be unblinded, and the control arm will be given the opportunity of cross-over.
Keyphrases
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- chronic pain
- physical activity
- peritoneal dialysis
- prognostic factors
- randomized controlled trial
- neuropathic pain
- pain management
- patient reported outcomes
- spinal cord injury
- depressive symptoms
- cross sectional
- psychometric properties
- spinal cord
- gestational age