RBBP4-p300 axis modulates expression of genes essential for cell survival and is a potential target for therapy in glioblastoma.

Ann C MladekHuihuang YanShulan TianPaul A DeckerDanielle M BurgenskeKatrina BakkenZeng HuLihong HeMargaret A ConnorsBrett L CarlsonJonathan WilsonArchana Bommi-ReddyAndy ConeryJeanette E Eckel-PassowJann N SarkariaGaspar J Kitange

Published in: Neuro-oncology (2022)

RBBP4/p300 complex is present in GBM cells and is a potential therapeutic target.

Keyphrases

induced apoptosis
poor prognosis
cell cycle arrest
human health
genome wide
gene expression
risk assessment
dna methylation
transcription factor
cell proliferation
long non coding rna
oxidative stress
genome wide identification
replacement therapy
pi k akt