Building evidence on safety of endovascular thrombectomy for patients under anticoagulation with vitamin K antagonists.
Li GaoXiaowei SunPei-Ying LiPublished in: CNS neuroscience & therapeutics (2024)
A recent study by Brian Mac Grory and colleagues investigated the safety of endovascular thrombectomy (EVT) among patients under vitamin K antagonists (VKAs) use within 7 days prior to hospital admission. Through this retrospective, observational cohort study, they found prior VKA use did not increase the risk of symptomatic intracranial hemorrhage (sICH) overall. However, recent VKA use with a presenting international normalized ratio (INR) > 1.7 was associated with a significantly increased risk of sICH. Future large-scale randomized controlled trials should be conducted to further clarify the effects and feasibility of EVT therapy in ischemic stroke patients under anticoagulation.
Keyphrases
- end stage renal disease
- atrial fibrillation
- randomized controlled trial
- venous thromboembolism
- acute ischemic stroke
- ejection fraction
- newly diagnosed
- emergency department
- chronic kidney disease
- healthcare
- cross sectional
- stem cells
- oxidative stress
- patient reported outcomes
- optical coherence tomography
- subarachnoid hemorrhage