Alda-1 ameliorates air embolism-induced acute lung injury.

Shu-Yu WuShi-Jye ChuShih-En TangHsin-Ping PaoWen-I Liao

Published in: International journal of immunopathology and pharmacology (2023)

Alda-1 shows promise in mitigating AE-induced ALI, possibly through the upregulation of ALDH2 expression and suppression of the PI3K/Akt and NF-κB signaling pathways. Further research is warranted to validate these findings and to explore their translational potential in human subjects.

Keyphrases

signaling pathway
high glucose
endothelial cells
poor prognosis
diabetic rats
lps induced
oxidative stress
pi k akt
drug induced
mouse model
risk assessment
machine learning
binding protein
inflammatory response
big data
nuclear factor
pluripotent stem cells