Longitudinal retinal imaging study of newly diagnosed relapsing-remitting multiple sclerosis in Scottish population: baseline and 12 months follow-up profile of FutureMS retinal imaging cohort.
Yingdi ChenJuan LarrazMichael WongPatrick KearnsFraser BrownSarah-Jane MartinPeter ConnickNiall MacDougallChristine WeaverBaljean DhillonSiddharthan ChandranPublished in: BMJ open ophthalmology (2022)
The FutureMS retinal imaging study aims to demonstrate that patient with MS present with different extent of retinal abnormalities that can be captured by retinal imaging modalities such as OCT soon after diagnosis. These changes may sensitively mirror the brain atrophy or serve as predictors for disease activity. By developing sensitive, quantifiable and objective retinal biomarkers, FutureMS retinal imaging study will provide an opportunity to stratify patient with MS at an early stage and support future therapeutic strategies for a better outcome.
Keyphrases
- multiple sclerosis
- optical coherence tomography
- diabetic retinopathy
- high resolution
- disease activity
- optic nerve
- early stage
- rheumatoid arthritis
- systemic lupus erythematosus
- mass spectrometry
- white matter
- rheumatoid arthritis patients
- squamous cell carcinoma
- photodynamic therapy
- cross sectional
- juvenile idiopathic arthritis