Blood culture-negative infective endocarditis: a worse outcome? Results from a large multicentre retrospective Spanish cohort study.
Lorenzo Roberto SuardiArístides de AlarcónMaría Victoria GarcíaAntonio Plata CiezarCarmen Hidalgo TenorioFrancisco Javier Martinez-MarcosElena Concejo-MartínezJavier De la Torre LimaDavid Vinuesa GarcíaRafael Luque MárquezGuillermo OjedaJosé M Reguera IglesiasJosé M LomasLuis E Lopez-Cortesnull nullPublished in: Infectious diseases (London, England) (2021)
In our cohort, BCNIE was not associated to greater in-hospital mortality based in multivariate Cox regression models. The variables most frequently associated with mortality were indicated but not performed surgery (aHR = 2.48, 95% CI 1.73-3.56, p < .001), septic shock (aHR = 2.24, 95% CI 1.68-2.99, p < .001), age over 65 years (aHR = 1.88, 95% CI 1.40-2.52, p < .001) and complicated endocarditis (aHR = 1.79, 95% CI 1.36-2.37, p < .001).