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Advanced strategies for development of vaccines against human bacterial pathogens.

Abhinay SharmaPooja SandujaAparna AnandPooja MahajanCarlos A GuzmanPuja YadavAmit AwasthiEmanuel HanskiMeenakshi DuaAtul Kumar Johri
Published in: World journal of microbiology & biotechnology (2021)
Infectious diseases are one of the main grounds of death and disabilities in human beings globally. Lack of effective treatment and immunization for many deadly infectious diseases and emerging drug resistance in pathogens underlines the need to either develop new vaccines or sufficiently improve the effectiveness of currently available drugs and vaccines. In this review, we discuss the application of advanced tools like bioinformatics, genomics, proteomics and associated techniques for a rational vaccine design.
Keyphrases
  • infectious diseases
  • endothelial cells
  • induced pluripotent stem cells
  • randomized controlled trial
  • systematic review
  • gram negative
  • pluripotent stem cells
  • mass spectrometry
  • single cell
  • antimicrobial resistance