Safety and pharmacokinetics of the Fc-modified HIV-1 human monoclonal antibody VRC01LS: A Phase 1 open-label clinical trial in healthy adults.
Martin R GaudinskiEmily E CoatesKatherine V HouserGrace L ChenGalina YamshchikovJamie G SaundersLaSonji A HolmanIngelise GordonSarah PlummerCynthia S HendelMichelle Conan-CibottiMargarita Gomez LorenzoSandra SitarKevin CarltonCarolyn LaurencotRobert T BailerSandeep NarpalaAdrian B McDermottAryan M NamboodiriJanardan P PandeyRichard M SchwartzZonghui HuRichard A KoupEdmund V CapparelliBarney S GrahamJohn R MascolaJulie E Ledgerwoodnull nullPublished in: PLoS medicine (2018)
ClinicalTrials.gov NCT02599896.
Keyphrases
- monoclonal antibody
- open label
- clinical trial
- phase ii
- endothelial cells
- antiretroviral therapy
- hiv positive
- phase iii
- study protocol
- hiv infected
- human immunodeficiency virus
- hiv testing
- hepatitis c virus
- induced pluripotent stem cells
- hiv aids
- phase ii study
- men who have sex with men
- double blind
- pluripotent stem cells
- randomized controlled trial
- south africa