RSO can reduce the expression of pro-inflammatory mediators, oxidative factors involved in injured vascular endothelial cells, exhibiting anti-inflammatory and antioxidant properties HUVECs exposed to ox-LDL. In addition, it may alleviate endothelial cell damage by inhibiting the TLR4/NF-κB signaling pathway.
Keyphrases
- endothelial cells
- signaling pathway
- anti inflammatory
- pi k akt
- oxidative stress
- high glucose
- poor prognosis
- induced apoptosis
- epithelial mesenchymal transition
- vascular endothelial growth factor
- toll like receptor
- inflammatory response
- low density lipoprotein
- immune response
- lps induced
- nuclear factor
- binding protein
- fatty acid