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Orthogonal genome editing and transcriptional activation in tomato using CRISPR-Combo systems.

Innocent ByiringiroChangtian PanYiping Qi
Published in: Plant cell reports (2024)
The CRISPR-Combo systems (Cas9-Combo and CBE-Combo) are designed for comprehensive genetic manipulation, enabling Cas9-based targeted mutagenesis or cytosine base editing with simultaneous gene activation in tomato stable lines.
Keyphrases
  • crispr cas
  • genome editing
  • genome wide
  • copy number
  • transcription factor
  • cancer therapy
  • oxidative stress
  • heat shock
  • genome wide analysis