Poor prognosis of bladder cancer patients with occult lymph node metastases treated with neoadjuvant chemotherapy.
Eugene K ChaJohn P SfakianosRanjit SukhuAlyssa M YeeDaniel D SjobergBernard H BochnerPublished in: BJU international (2018)
LN-positive patients previously treated with NAC have a poor prognosis, significantly worse than LN-positive patients subsequently treated with AC, and should be considered for protocols using sandwich chemotherapy approaches or novel agents. These results should be considered in the interpretation of and stratification for clinical trials.
Keyphrases
- poor prognosis
- neoadjuvant chemotherapy
- lymph node
- newly diagnosed
- end stage renal disease
- long non coding rna
- clinical trial
- ejection fraction
- chronic kidney disease
- locally advanced
- peritoneal dialysis
- randomized controlled trial
- squamous cell carcinoma
- sentinel lymph node
- patient reported outcomes
- early stage
- study protocol