What is the aetiology of dysnatraemia in COVID-19 and how is this related to outcomes in patients admitted during earlier and later COVID-19 waves? A multicentre, retrospective observational study in 11 Dutch hospitals.

Lianne R de HaanMarije Ten WoldeMartijn BeudelRik H G Olde EngberinkBrent AppelmanEsther K Haspels-HogervorstDaisy RuschNiels C Gritters van den OeverSuat SimsekNienke PaternotteJoop P van den BerghCaroline E WyersMartijn D de KruifTom DormansHazra MoeniralamNeyma BokhizzouKees BrinkmanRenee Doumanull null

Published in: BMJ open (2023)

Hypernatraemia at presentation was associated with adverse outcomes in patients with COVID-19. Hypovolaemic hyponatraemia was found to be the most common aetiology of hyponatraemia. Hyponatraemia of unknown aetiology was associated with a higher risk for ICU admission and intubation and longer duration of admission.

Keyphrases

coronavirus disease
sars cov
emergency department
cross sectional
intensive care unit
healthcare
clinical trial
cardiac arrest
respiratory syndrome coronavirus
study protocol
randomized controlled trial
case report
mechanical ventilation
double blind
metabolic syndrome
acute respiratory distress syndrome