Vitamin D attenuates biofilm-associated infections via immunomodulation and cathelicidin expression: a narrative review.
Ruby BensonMazhuvancherry Kesavan UnnikrishnanShilia Jacob KurianSaleena Ummer VelladathGabriel Sunil RodriguesRaghu Chandrashekar HariharapuraAnju MuraleedharanDinesh Bangalore VenkateshiahBarnini BanerjeeChiranjay MukhopadhyayAieshel Serafin JohnsonMurali MunisamyMahadev RaoBenson Mathai KochikuzhyilSonal Sekhar MirajPublished in: Expert review of anti-infective therapy (2022)
Although vitamin D deficiency has been associated with infections by biofilm producing microbes, comprehensive clinical trials in various ethnicities are required to understand the likely relationships between vitamin D receptor gene expression, cathelicidin levels and infection outcome. Current evidence hypothesizes that maintaining normal vitamin D level can help prevent and treat these infections.