Prevalence of treatment resistance and clozapine use in early intervention services.

Imogen StokesSiân Lowri GriffithsRowena JonesLinda EverardPeter B JonesDavid FowlerJoanne HodgekinsTim AmosNick FreemantleVimal SharmaMax MarshallSwaran P SinghMax BirchwoodRachel Upthegrove

Published in: BJPsych open (2020)

Prevalent treatment resistance was observed in UK EIP services, but prescription of polypharmacy was much more common than clozapine. Significant delays in the commencement of clozapine may reflect a missed opportunity to promote recovery in this critical period.

Keyphrases

healthcare
primary care
randomized controlled trial
mental health
risk factors
emergency department
cross sectional