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Clinical and neuropsychological profile of patients with dementia and chronic traumatic encephalopathy.

Christian LoBueJeff SchaffertC Munro CullumMatthew E PetersNyaz DidehbaniJohn HartCharles L White
Published in: Journal of neurology, neurosurgery, and psychiatry (2020)
CTE pathology was rare in a large multicentre national dataset, and when present, was accompanied by AD and TDP-43 pathologies. CTE was not associated with a different clinical presentation from AD or with greater cognitive impairment or neurobehavioral symptoms. These findings suggest that CTE may not have a distinct clinical profile when other neuropathologic processes are coexistent with CTE pathology.
Keyphrases
  • cognitive impairment
  • mild cognitive impairment
  • spinal cord injury
  • clinical trial
  • early onset
  • randomized controlled trial
  • study protocol
  • depressive symptoms
  • cross sectional
  • physical activity