Examining expertise: Synthetic biology experts' perceptions of risk, benefit, and the public for research and applications regulation.

Scientific experts can play an important role in decision-making surrounding policy for technical and value-laden issues, often in contexts that directly affect lay publics. Yet little is known about what characterizes scientific experts who want lay public involvement in decision-making. In this study, we examine how synthetic biology experts' perceptions of risks, benefits, and ambivalence for synthetic biology relate to views of lay publics, deference to scientific authority, and regulations. We analyzed survey data of researchers in the United States, who published academic articles relating to synthetic biology from 2000 to 2015. Scientific experts who see less risk and are more deferent to scientific authority appear to favor a more closed system in which regulations are sufficient, citizens should not be involved, and scientists know best. Conversely, scientific experts who see more potential for risk and see the public as bringing a valuable perspective appear to favor a more open, inclusive system.