Systematic Characterization of Antibody-Drug Conjugate Targets in Central Nervous System Tumors.
Shannon CoyJong Suk LeeSabrina J ChanTerri WooJacquelyn JonesSanda AlexandrescuPatrick Y WenPeter Karl SorgerKeith L LigonSandro SantagataPublished in: Neuro-oncology (2023)
CNS tumors exhibit subtype-specific expression of ADC targets including several FDA-approved for other indications. Clinical trials of ADCs in CNS tumors may therefore be warranted.