Repeatability and reproducibility of ADC measurements: a prospective multicenter whole-body-MRI study.
Nicolas F MichouxJakub W CerankaJef VandemeulebrouckeFrank PeetersPierre LuJulie AbsilPerrine TriqueneauxYan LiuLaurence ColletteInneke WillekensCarola BrussaardOlivier DebeirStephan HahnHubert RaeymaekersJohan de MeyThierry MetensFrédéric E LecouvetPublished in: European radiology (2021)
• The present study showed the range of R&R of ADC in WB-MRI that may be achieved in a multicenter framework when a standardized protocol is deployed. • R&R was not influenced by the site of acquisition of DW images. • Clinically significant changes in ADC measured in a multicenter WB-MRI protocol performed with the same type of MRI scanner must be superior to 12% (cerebrum white matter), 16% (paraspinal muscle), 22% (renal cortex), 26% (central zone and peripheral zone of prostate), 29% (renal medulla), 35% (liver), 45% (spleen), 50% (posterior iliac crest), 66% (L5 vertebra), 68% (femur), and 94% (acetabulum) to be detected with a 95% confidence level.
Keyphrases
- diffusion weighted imaging
- contrast enhanced
- diffusion weighted
- magnetic resonance imaging
- white matter
- randomized controlled trial
- prostate cancer
- cross sectional
- magnetic resonance
- deep learning
- double blind
- machine learning
- skeletal muscle
- clinical trial
- bone mineral density
- functional connectivity
- convolutional neural network
- body composition