Reduced translation efficiency due to novel splicing variants in 5' untranslated region and identification of novel cis-regulatory elements in canine and human BRCA2.
Yasunaga YoshikawaHajime KozumaMasami MorimatsuKaori SugawaraKoichi OrinoPublished in: BMC molecular and cell biology (2021)
This study demonstrates that BRCA2 expression level is regulated via 5' UTR splicing variants and that the BRCA2 intron 1 region harbors cis-regulatory elements.