Impact of Intravenous Lipid Emulsions Containing Fish Oil on Clinical Outcomes in Critically Ill Surgical Patients: A Literature Review.

Samantha HoneywellRena ZeligDiane Rigassio Radler

Published in: Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition (2018)

A fish oil (FO)-containing intravenous lipid emulsion (ILE; FO ILE) has been approved for use in the United States; however, similar formulations have been used throughout Europe and China in intensive care units since the 1990s. This literature review evaluates the evidence regarding the effectiveness of FO ILE on clinical outcomes in the critically ill surgical patient population. The review of available evidence demonstrates that ILEs containing FO lower triglyceride concentrations, inflammatory markers, and liver function enzymes, and improve morbidity and mortality outcomes in critically ill surgical patients.

Keyphrases

case report
fatty acid
intensive care unit
high dose
randomized controlled trial
systematic review
low dose
mechanical ventilation
metabolic syndrome
acute respiratory distress syndrome
drug administration
low density lipoprotein