Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma.
Shawn M DavidsonDaniel R SchmidtJulia E HeymanJames P O'BrienAmy C LiuWilliam J IsraelsenTalya L DaytonRaghav SehgalRoderick T BronsonElizaveta FreinkmanHoward H MakGiuseppe Nicolò FanelliScott MalstromGary BellingerArkaitz CarracedoPier Paolo PandolfiKevin Dale CourtneyAbhishek JhaRonald A DePinhoJames W HornerCraig J ThomasLewis C CantleyMassimo LodaMatthew G Vander HeidenPublished in: Cancer research (2022)
Differential expression of PKM1 and PKM2 impacts prostate tumorigenesis and suggests a potential therapeutic vulnerability in prostate cancer.