Matthew G Vander Heiden (Matthew Vander Heiden)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 113

Top Venues

bioRxiv : the preprint server for biology

Nature

Nature communications

eLife

This page only lists publications with an associated author ORCID identifier.

Publications

Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Anderson Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Clary B Clish, Alexander Muir, W Kimryn Rathmell, Jeffrey C Rathmell, Matthew G Vander Heiden
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. eLife 13 (2024)
Ting Dong, Guangan Hu, Zhongqi Fan, Huirui Wang, Yinghui Gao, Sisi Wang, Hao Xu, Micheal B Yaffe, Matthew G Vander Heiden, Guo-Yue Lv, Jianzhu Chen
Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis. Nature communications 15 (1) (2024)
Zhaoqi Li, Muhammad Bin Munim, Daniel A Sharygin, Brooke J Bevis, Matthew G Vander Heiden
Understanding the Warburg Effect in Cancer. Cold Spring Harbor perspectives in medicine (2024)
Adrienne A Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Jane Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai
Why do patients with cancer die? Nature reviews. Cancer 24 (8) (2024)
Xiaofeng A Su, Konrad H Stopsack, Daniel R Schmidt, Duanduan Ma, Zhe Li, Paul A Scheet, Kathryn L Penney, Tamara L Lotan, Wassim Abida, Elise G DeArment, Kate Lu, Thomas Janas, Sofia Hu, Matthew G Vander Heiden, Massimo Loda, Monica Boselli, Angelika Amon, Lorelei A Mucci
RAD21 promotes oncogenesis and lethal progression of prostate cancer. Proceedings of the National Academy of Sciences of the United States of America 121 (36) (2024)
Christopher Chidley, Alicia M Darnell, Benjamin L Gaudio, Evan C Lien, Anna M Barbeau, Matthew G Vander Heiden, Peter Karl Sorger
A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments. Nature cell biology (2024)
Ting Dong, Guangan Hu, Zhongqi Fan, Huirui Wang, Yinghui Gao, Sisi Wang, Hao Xu, Micheal B Yaffe, Matthew G Vander Heiden, Guo-Yue Lv, Jianzhu Chen
Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis. Nature communications 15 (1) (2024)
Christopher Chidley, Alicia M Darnell, Benjamin L Gaudio, Evan C Lien, Anna M Barbeau, Matthew G Vander Heiden, Peter Karl Sorger
A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments. Nature cell biology 26 (5) (2024)
Christopher Chidley, Alicia M Darnell, Benjamin L Gaudio, Evan C Lien, Anna M Barbeau, Matthew G Vander Heiden, Peter Karl Sorger
A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments. Nature cell biology 26 (5) (2024)
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Andrew T Chan, Alexander Muir, W Kimryn Rathmell, Jeffrey C Rathmell, Matthew G Vander Heiden
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. bioRxiv : the preprint server for biology (2024)
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Andrew T Chan, Alexander Muir, W Kimryn Rathmell, Jeffrey C Rathmell, Matthew G Vander Heiden
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. bioRxiv : the preprint server for biology (2024)
Adrienne A Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Jane Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai
Why do patients with cancer die? Nature reviews. Cancer 24 (8) (2024)
Shijie Liu, Seth T Gammon, Lin Tan, Yaqi Gao, Kyoungmin Kim, Ian K Williamson, Janet Pham, Angela Davidian, Radhika Khanna, Benjamin D Gould, Rebecca Salazar, Heidi Vitrac, An Dinh, Evan C Lien, Francisca N de L Vitorino, Joanna M Gongora, Sara A Martinez, Czer S C Lawrence, Evan P Kransdorf, David Leffer, Blake Hanson, Benjamin A Garcia, Matthew G Vander Heiden, Philip L Lorenzi, Heinrich Taegtmeyer, David Piwnica-Worms, James F Martin, Anja Karlstaedt
ATP-dependent citrate lyase Drives Left Ventricular Dysfunction by Metabolic Remodeling of the Heart. bioRxiv : the preprint server for biology (2024)
Xiaofeng A Su, Konrad H Stopsack, Daniel R Schmidt, Duanduan Ma, Zhe Li, Paul A Scheet, Kathryn L Penney, Tamara L Lotan, Wassim Abida, Elise G DeArment, Kate Lu, Thomas Janas, Sofia Hu, Matthew G Vander Heiden, Massimo Loda, Monica Boselli, Angelika Amon, Lorelei A Mucci
RAD21 promotes oncogenesis and lethal progression of prostate cancer. Proceedings of the National Academy of Sciences of the United States of America 121 (36) (2024)
Sharanya Sivanand, Yetis Gultekin, Peter S Winter, Sidney Y Vermeulen, Konstantine M Tchourine, Keene L Abbott, Laura V Danai, Florian Gourgue, Brian T Do, Kayla Crowder, Tenzin Kunchok, Allison N Lau, Alicia M Darnell, Alexandria Jefferson, Satoru Morita, Dan G Duda, Andrew J Aguirre, Brian M Wolpin, Nicole Henning, Virginia Spanoudaki, Laura Maiorino, Darrell J Irvine, Ömer H Yilmaz, Caroline A Lewis, Dennis Vitkup, Alex K Shalek, Matthew G Vander Heiden
Cancer tissue of origin constrains the growth and metabolism of metastases. Nature metabolism (2024)
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Anderson I Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Andrew T Chan, Alexander Muir, W Kimryn Rathmell, Jeffrey C Rathmell, Matthew G Vander Heiden
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. bioRxiv : the preprint server for biology (2024)
Adrienne A Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Jane Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai
Why do patients with cancer die? Nature reviews. Cancer (2024)
Adrienne A Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Jane Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai
Why do patients with cancer die? Nature reviews. Cancer 24 (8) (2024)
Sun Jin Moon, Anush Chiappino-Pepe, Wentao Dong, Joanne K Kelleher, Matthew G Vander Heiden, Gregory Stephanopoulos, Hadley D Sikes
NADPH composite index analysis quantifies the relationship between compartmentalized NADPH dynamics and growth rates in cancer cells. bioRxiv : the preprint server for biology (2024)
Christopher Chidley, Alicia M Darnell, Benjamin L Gaudio, Evan C Lien, Anna M Barbeau, Matthew G Vander Heiden, Peter Karl Sorger
A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments. Nature cell biology 26 (5) (2024)
Ting Dong, Guangan Hu, Zhongqi Fan, Huirui Wang, Yinghui Gao, Sisi Wang, Hao Xu, Micheal B Yaffe, Matthew G Vander Heiden, Guo-Yue Lv, Jianzhu Chen
Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis. Nature communications 15 (1) (2024)
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Anderson Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Clary B Clish, Alexander Muir, W Kimryn Rathmell, Jeffrey C Rathmell, Matthew G Vander Heiden
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. eLife 13 (2024)
Christopher Chidley, Alicia M Darnell, Benjamin L Gaudio, Evan C Lien, Anna M Barbeau, Matthew G Vander Heiden, Peter Karl Sorger
A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments. Nature cell biology (2024)
Christopher Chidley, Alicia M Darnell, Benjamin L Gaudio, Evan C Lien, Anna M Barbeau, Matthew G Vander Heiden, Peter Karl Sorger
A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments. Nature cell biology 26 (5) (2024)
Shinya Imada, Saleh Khawaled, Heaji Shin, Sven W Meckelmann, Charles A Whittaker, Renan Oliveira Corrêa, Chiara Alquati, Yixin Lu, Guodong Tie, Dikshant Pradhan, Gizem Calibasi Kocal, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler, Pia Wittenhofer, Jonathan Krystkiewicz, Oliver J Schmitz, Jatin Roper, Marco Aurelio Ramirez Vinolo, Luigi Ricciardiello, Evan C Lien, Matthew G Vander Heiden, Ramesh A Shivdasani, Chia-Wei Cheng, Alpaslan Tasdogan, Ömer H Yilmaz
Short-term post-fast refeeding enhances intestinal stemness via polyamines. Nature (2024)
Adrienne A Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Jane Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai
Why do patients with cancer die? Nature reviews. Cancer 24 (8) (2024)
Ting Dong, Guangan Hu, Zhongqi Fan, Huirui Wang, Yinghui Gao, Sisi Wang, Hao Xu, Micheal B Yaffe, Matthew G Vander Heiden, Guo-Yue Lv, Jianzhu Chen
Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis. Nature communications 15 (1) (2024)
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Andrew T Chan, Alexander Muir, W Kimryn Rathmell, Jeffrey C Rathmell, Matthew G Vander Heiden
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. bioRxiv : the preprint server for biology (2024)
Ting Dong, Guangan Hu, Zhongqi Fan, Huirui Wang, Yinghui Gao, Sisi Wang, Hao Xu, Micheal B Yaffe, Matthew G Vander Heiden, Guo-Yue Lv, Jianzhu Chen
Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis. Nature communications 15 (1) (2024)
Adrienne A Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Jane Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai
Why do patients with cancer die? Nature reviews. Cancer 24 (8) (2024)
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Anderson Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Clary B Clish, Alexander Muir, W Kimryn Rathmell, Jeffrey C Rathmell, Matthew G Vander Heiden
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. eLife 13 (2024)
Tigist Y Tamir, Shreya Chaudhary, Annie X Li, Sonia E Trojan, Cameron T Flower, Paula Vo, Yufei Cui, Jeffrey C Davis, Rachit S Mukkamala, Francesca N Venditti, Alissandra L Hillis, Alex Toker, Matthew G Vander Heiden, Jessica Brooke Spinelli, Norman J Kennedy, Roger J Davis, Forest M White
Structural and systems characterization of phosphorylation on metabolic enzymes identifies sex-specific metabolic reprogramming in obesity. bioRxiv : the preprint server for biology (2024)
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Anderson I Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Andrew T Chan, Alexander Muir, W Kimryn Rathmell, Jeffrey C Rathmell, Matthew G Vander Heiden
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. bioRxiv : the preprint server for biology (2024)
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Andrew T Chan, Alexander Muir, W Kimryn Rathmell, Jeffrey C Rathmell, Matthew G Vander Heiden
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. bioRxiv : the preprint server for biology (2024)
Adrienne A Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Jane Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai
Why do patients with cancer die? Nature reviews. Cancer (2024)
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Anderson Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Clary B Clish, Alexander Muir, W Kimryn Rathmell, Jeffrey C Rathmell, Matthew G Vander Heiden
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. eLife 13 (2024)
Adrienne A Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Jane Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai
Why do patients with cancer die? Nature reviews. Cancer 24 (8) (2024)
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Anderson Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Clary B Clish, Alexander Muir, W Kimryn Rathmell, Jeffrey C Rathmell, Matthew G Vander Heiden
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. eLife 13 (2024)
Ting Dong, Guangan Hu, Zhongqi Fan, Huirui Wang, Yinghui Gao, Sisi Wang, Hao Xu, Micheal B Yaffe, Matthew G Vander Heiden, Guo-Yue Lv, Jianzhu Chen
Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis. Nature communications 15 (1) (2024)
Keene L Abbott, Ahmed Ali, Dominick Casalena, Brian T Do, Raphael Ferreira, Jaime H Cheah, Christian K Soule, Amy Deik, Tenzin Kunchok, Daniel R Schmidt, Steffen Renner, Sophie E Honeder, Michelle Wu, Sze Ham Chan, Tenzin Tseyang, Daniel Greaves, Peggy P Hsu, Christopher W Ng, Chelsea J Zhang, Ali Farsidjani, Iva Monique T Gramatikov, Nicholas J Matheson, Caroline A Lewis, Clary B Clish, Matthew G Rees, Jennifer A Roth, Lesley Mathews Griner, Alexander Muir, Douglas S Auld, Matthew G Vander Heiden
Screening in serum-derived medium reveals differential response to compounds targeting metabolism. bioRxiv : the preprint server for biology (2023)
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Andrew T Chan, Alexander Muir, W Kimryn Rathmell, Jeffrey C Rathmell, Matthew G Vander Heiden
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. bioRxiv : the preprint server for biology (2023)
Evan C Lien, Ngoc Vu, Anna M Westermark, Laura V Danai, Allison N Lau, Yetiş Gültekin, Matthew A Kukurugya, Bryson D Bennett, Matthew G Vander Heiden
Effects of aging on glucose and lipid metabolism in mice. bioRxiv : the preprint server for biology (2023)
Azucena Ramos, Catherine E Koch, Yunpeng Liu-Lupo, Riley D Hellinger, Taeyoon Kyung, Keene L Abbott, Julia Fröse, Daniel Goulet, Khloe S Gordon, Keith P Eidell, Paul Leclerc, Charles A Whittaker, Rebecca C Larson, Audrey J Muscato, Kathleen B Yates, Juan Dubrot, John G Doench, Aviv Regev, Matthew G Vander Heiden, Marcela V Maus, Robert T Manguso, Michael E Birnbaum, Michael T Hemann
Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening. Nature communications 14 (1) (2023)
Ana Babic, Michael H Rosenthal, Tilak K Sundaresan, Natalia Khalaf, Valerie Lee, Lauren K Brais, Maureen Loftus, Leah Caplan, Sarah Denning, Anamol Gurung, Joanna Harrod, Khoschy Schawkat, Chen Yuan, Qiao-Li Wang, Alice A Lee, Leah H Biller, Matthew B Yurgelun, Kimmie Ng, Jonathan A Nowak, Andrew J Aguirre, Sangeeta N Bhatia, Matthew G Vander Heiden, Stephen K Van den Eeden, Bette J Caan, Brian M Wolpin
Adipose tissue and skeletal muscle wasting precede clinical diagnosis of pancreatic cancer. Nature communications 14 (1) (2023)
Kevin G Hicks, Ahmad A Cluntun, Heidi L Schubert, Sean R Hackett, Jordan A Berg, Paul G Leonard, Mariana A A Aleixo, Youjia Zhou, Alex J Bott, Sonia R Salvatore, Fei Chang, Aubrie Blevins, Paige Barta, Samantha Tilley, Aaron Leifer, Andrea Guzman, Ajak Arok, Sarah Fogarty, Jacob M Winter, Hee Chul Ahn, Karen N Allen, Samuel Block, Iara Aimê Cardoso, Jianping Ding, Ingrid Dreveny, William C Gasper, Quinn Ho, Atsushi Matsuura, Michael J Palladino, Sabin Prajapati, Pengkai Sun, Kai Tittmann, Dean R Tolan, Judith Unterlass, Andrew P VanDemark, Matthew G Vander Heiden, Bradley A Webb, Cai-Hong Yun, Pengkai Zhao, Bei Wang, Francisco J Schopfer, Christopher P Hill, Maria Cristina Nonato, Florian L Muller, James Eric Cox, Jared Rutter
Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase. Science (New York, N.Y.) 379 (6636) (2023)
Amandine Moretton, Savvas Kourtis, Antoni Gañez Zapater, Chiara Calabrò, Maria Lorena Espinar Calvo, Frédéric Fontaine, Evangelia Darai, Etna Abad Cortel, Samuel Block, Laura Pascual-Reguant, Natalia Pardo, Ritobrata Ghose, Matthew G Vander Heiden, Ana Janic, André C Müller, Joanna I Loizou, Sara Sdelci
A metabolic map of the DNA damage response identifies PRDX1 in the control of nuclear ROS scavenging and aspartate availability. Molecular systems biology (2023)
Caroline R Bartman, Daniel R Weilandt, Yihui Shen, Won Dong Lee, Yujiao Han, Tara TeSlaa, Connor S R Jankowski, Laith Samarah, Noel R Park, Victoria da Silva-Diz, Maya Aleksandrova, Yetis Gultekin, Argit Marishta, Lin Wang, Lifeng Yang, Asael Roichman, Vrushank Bhatt, Taijin Lan, Zhixian Hu, Xi Xing, Wenyun Lu, Shawn M Davidson, Martin Wühr, Matthew G Vander Heiden, Daniel Herranz, Jessie Yanxiang Guo, Yibin Kang, Joshua D Rabinowitz
Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature 614 (7947) (2023)
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Andrew T Chan, Alexander Muir, W Kimryn Rathmell, Jeffrey C Rathmell, Matthew G Vander Heiden
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. bioRxiv : the preprint server for biology (2023)
Caroline R Bartman, Daniel R Weilandt, Yihui Shen, Won Dong Lee, Yujiao Han, Tara TeSlaa, Connor S R Jankowski, Laith Samarah, Noel R Park, Victoria da Silva-Diz, Maya Aleksandrova, Yetis Gultekin, Argit Marishta, Lin Wang, Lifeng Yang, Asael Roichman, Vrushank Bhatt, Taijin Lan, Zhixian Hu, Xi Xing, Wenyun Lu, Shawn M Davidson, Martin Wühr, Matthew G Vander Heiden, Daniel Herranz, Jessie Yanxiang Guo, Yibin Kang, Joshua D Rabinowitz
Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature (2023)
Kailash Chandra Mangalhara, Siva Karthik Varanasi, Melissa A Johnson, Mannix J Burns, Gladys R Rojas, Pau B Esparza Moltó, Alva G Sainz, Nimesha Tadepalle, Keene L Abbott, Gaurav Mendiratta, Dan Chen, Yagmur Farsakoglu, Tenzin Kunchok, Filipe Araujo Hoffmann, Bianca Parisi, Mercedes Rincon, Matthew G Vander Heiden, Marcus W Bosenberg, Diana C Hargreaves, Susan M Kaech, Gerald S Shadel
Manipulating mitochondrial electron flow enhances tumor immunogenicity. Science (New York, N.Y.) 381 (6664) (2023)
Caroline R Bartman, Daniel R Weilandt, Yihui Shen, Won Dong Lee, Yujiao Han, Tara TeSlaa, Connor S R Jankowski, Laith Samarah, Noel R Park, Victoria da Silva-Diz, Maya Aleksandrova, Yetis Gultekin, Argit Marishta, Lin Wang, Lifeng Yang, Asael Roichman, Vrushank Bhatt, Taijin Lan, Zhixian Hu, Xi Xing, Wenyun Lu, Shawn M Davidson, Martin Wühr, Matthew G Vander Heiden, Daniel Herranz, Jessie Yanxiang Guo, Yibin Kang, Joshua D Rabinowitz
Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature 614 (7947) (2023)
Evan C Lien, Ngoc Vu, Anna M Westermark, Laura V Danai, Allison N Lau, Yetiş Gültekin, Matthew A Kukurugya, Bryson D Bennett, Matthew G Vander Heiden
Effects of aging on glucose and lipid metabolism in mice. bioRxiv : the preprint server for biology (2023)
Jung-Kuei Chen, Karl A Merrick, Yi Wen Kong, Anita Izrael-Tomasevic, George Eng, Erika D Handly, Jesse C Patterson, Ian G Cannell, Lucia Suarez-Lopez, Aaron M Hosios, Anh Dinh, Donald S Kirkpatrick, Kebing Yu, Christopher M Rose, Jonathan M Hernandez, Haeun Hwangbo, Adam C Palmer, Matthew G Vander Heiden, Ömer H Yilmaz, Micheal B Yaffe
An RNA Damage Response Network Mediates the Lethality of 5-FU in Clinically Relevant Tumor Types. bioRxiv : the preprint server for biology (2023)
Caroline R Bartman, Daniel R Weilandt, Yihui Shen, Won Dong Lee, Yujiao Han, Tara TeSlaa, Connor S R Jankowski, Laith Samarah, Noel R Park, Victoria da Silva-Diz, Maya Aleksandrova, Yetis Gultekin, Argit Marishta, Lin Wang, Lifeng Yang, Asael Roichman, Vrushank Bhatt, Taijin Lan, Zhixian Hu, Xi Xing, Wenyun Lu, Shawn M Davidson, Martin Wühr, Matthew G Vander Heiden, Daniel Herranz, Jessie Yanxiang Guo, Yibin Kang, Joshua D Rabinowitz
Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature (2023)
Evan C Lien, Ngoc Vu, Anna M Westermark, Laura V Danai, Allison N Lau, Yetiş Gültekin, Matthew A Kukurugya, Bryson D Bennett, Matthew G Vander Heiden
Effects of aging on glucose and lipid metabolism in mice. bioRxiv : the preprint server for biology (2023)
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Andrew T Chan, Alexander Muir, W Kimryn Rathmell, Jeffrey C Rathmell, Matthew G Vander Heiden
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. bioRxiv : the preprint server for biology (2023)
Jung-Kuei Chen, Karl A Merrick, Yi Wen Kong, Anita Izrael-Tomasevic, George Eng, Erika D Handly, Jesse C Patterson, Ian G Cannell, Lucia Suarez-Lopez, Aaron M Hosios, Anh Dinh, Donald S Kirkpatrick, Kebing Yu, Christopher M Rose, Jonathan M Hernandez, Haeun Hwangbo, Adam C Palmer, Matthew G Vander Heiden, Ömer H Yilmaz, Micheal B Yaffe
An RNA Damage Response Network Mediates the Lethality of 5-FU in Clinically Relevant Tumor Types. bioRxiv : the preprint server for biology (2023)
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Andrew T Chan, Alexander Muir, W Kimryn Rathmell, Jeffrey C Rathmell, Matthew G Vander Heiden
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. bioRxiv : the preprint server for biology (2023)
Caroline R Bartman, Daniel R Weilandt, Yihui Shen, Won Dong Lee, Yujiao Han, Tara TeSlaa, Connor S R Jankowski, Laith Samarah, Noel R Park, Victoria da Silva-Diz, Maya Aleksandrova, Yetis Gultekin, Argit Marishta, Lin Wang, Lifeng Yang, Asael Roichman, Vrushank Bhatt, Taijin Lan, Zhixian Hu, Xi Xing, Wenyun Lu, Shawn M Davidson, Martin Wühr, Matthew G Vander Heiden, Daniel Herranz, Jessie Yanxiang Guo, Yibin Kang, Joshua D Rabinowitz
Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature (2023)
Caroline R Bartman, Daniel R Weilandt, Yihui Shen, Won Dong Lee, Yujiao Han, Tara TeSlaa, Connor S R Jankowski, Laith Samarah, Noel R Park, Victoria da Silva-Diz, Maya Aleksandrova, Yetis Gultekin, Argit Marishta, Lin Wang, Lifeng Yang, Asael Roichman, Vrushank Bhatt, Taijin Lan, Zhixian Hu, Xi Xing, Wenyun Lu, Shawn M Davidson, Martin Wühr, Matthew G Vander Heiden, Daniel Herranz, Jessie Yanxiang Guo, Yibin Kang, Joshua D Rabinowitz
Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature (2023)
Daniel R Schmidt, Iva Monique T Gramatikov, Allison Sheen, Christopher L Williams, Martina Hurwitz, Laura E Dodge, Edward Holupka, W S Kiger, Milton R Cornwall-Brady, Wei Huang, Howard H Mak, Kathleen S Cormier, Charlene Condon, Karl Dane Wittrup, Ömer H Yilmaz, Mary Ann Stevenson, Julian D Down, Scott R Floyd, Jatin Roper, Matthew G Vander Heiden
Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer. Communications medicine 3 (1) (2023)
Caroline R Bartman, Daniel R Weilandt, Yihui Shen, Won Dong Lee, Yujiao Han, Tara TeSlaa, Connor S R Jankowski, Laith Samarah, Noel R Park, Victoria da Silva-Diz, Maya Aleksandrova, Yetis Gultekin, Argit Marishta, Lin Wang, Lifeng Yang, Asael Roichman, Vrushank Bhatt, Taijin Lan, Zhixian Hu, Xi Xing, Wenyun Lu, Shawn M Davidson, Martin Wühr, Matthew G Vander Heiden, Daniel Herranz, Jessie Yanxiang Guo, Yibin Kang, Joshua D Rabinowitz
Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature 614 (7947) (2023)
Keene L Abbott, Ahmed Ali, Dominick Casalena, Brian T Do, Raphael Ferreira, Jaime H Cheah, Christian K Soule, Amy Deik, Tenzin Kunchok, Daniel R Schmidt, Steffen Renner, Sophie E Honeder, Michelle Wu, Sze Ham Chan, Tenzin Tseyang, Daniel Greaves, Peggy P Hsu, Christopher W Ng, Chelsea J Zhang, Ali Farsidjani, Iva Monique T Gramatikov, Nicholas J Matheson, Caroline A Lewis, Clary B Clish, Matthew G Rees, Jennifer A Roth, Lesley Mathews Griner, Alexander Muir, Douglas S Auld, Matthew G Vander Heiden
Screening in serum-derived medium reveals differential response to compounds targeting metabolism. bioRxiv : the preprint server for biology (2023)
Keene L Abbott, Ahmed Ali, Dominick Casalena, Brian T Do, Raphael Ferreira, Jaime H Cheah, Christian K Soule, Amy Deik, Tenzin Kunchok, Daniel R Schmidt, Steffen Renner, Sophie E Honeder, Michelle Wu, Sze Ham Chan, Tenzin Tseyang, Daniel Greaves, Peggy P Hsu, Christopher W Ng, Chelsea J Zhang, Ali Farsidjani, Iva Monique T Gramatikov, Nicholas J Matheson, Caroline A Lewis, Clary B Clish, Matthew G Rees, Jennifer A Roth, Lesley Mathews Griner, Alexander Muir, Douglas S Auld, Matthew G Vander Heiden
Screening in serum-derived medium reveals differential response to compounds targeting metabolism. bioRxiv : the preprint server for biology (2023)
Caroline R Bartman, Daniel R Weilandt, Yihui Shen, Won Dong Lee, Yujiao Han, Tara TeSlaa, Connor S R Jankowski, Laith Samarah, Noel R Park, Victoria da Silva-Diz, Maya Aleksandrova, Yetis Gultekin, Argit Marishta, Lin Wang, Lifeng Yang, Asael Roichman, Vrushank Bhatt, Taijin Lan, Zhixian Hu, Xi Xing, Wenyun Lu, Shawn M Davidson, Martin Wühr, Matthew G Vander Heiden, Daniel Herranz, Jessie Yanxiang Guo, Yibin Kang, Joshua D Rabinowitz
Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature 614 (7947) (2023)
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Andrew T Chan, Alexander Muir, W Kimryn Rathmell, Jeffrey C Rathmell, Matthew G Vander Heiden
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. bioRxiv : the preprint server for biology (2023)
Kevin G Hicks, Ahmad A Cluntun, Heidi L Schubert, Sean R Hackett, Jordan A Berg, Paul G Leonard, Mariana A A Aleixo, Youjia Zhou, Alex J Bott, Sonia R Salvatore, Fei Chang, Aubrie Blevins, Paige Barta, Samantha Tilley, Aaron Leifer, Andrea Guzman, Ajak Arok, Sarah Fogarty, Jacob M Winter, Hee Chul Ahn, Karen N Allen, Samuel Block, Iara Aimê Cardoso, Jianping Ding, Ingrid Dreveny, William C Gasper, Quinn Ho, Atsushi Matsuura, Michael J Palladino, Sabin Prajapati, Pengkai Sun, Kai Tittmann, Dean R Tolan, Judith Unterlass, Andrew P VanDemark, Matthew G Vander Heiden, Bradley A Webb, Cai-Hong Yun, Pengkai Zhao, Bei Wang, Francisco J Schopfer, Christopher P Hill, Maria Cristina Nonato, Florian L Muller, James Eric Cox, Jared Rutter
Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase. Science (New York, N.Y.) 379 (6636) (2023)
Caroline R Bartman, Daniel R Weilandt, Yihui Shen, Won Dong Lee, Yujiao Han, Tara TeSlaa, Connor S R Jankowski, Laith Samarah, Noel R Park, Victoria da Silva-Diz, Maya Aleksandrova, Yetis Gultekin, Argit Marishta, Lin Wang, Lifeng Yang, Asael Roichman, Vrushank Bhatt, Taijin Lan, Zhixian Hu, Xi Xing, Wenyun Lu, Shawn M Davidson, Martin Wühr, Matthew G Vander Heiden, Daniel Herranz, Jessie Yanxiang Guo, Yibin Kang, Joshua D Rabinowitz
Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature (2023)
Caroline R Bartman, Daniel R Weilandt, Yihui Shen, Won Dong Lee, Yujiao Han, Tara TeSlaa, Connor S R Jankowski, Laith Samarah, Noel R Park, Victoria da Silva-Diz, Maya Aleksandrova, Yetis Gultekin, Argit Marishta, Lin Wang, Lifeng Yang, Asael Roichman, Vrushank Bhatt, Taijin Lan, Zhixian Hu, Xi Xing, Wenyun Lu, Shawn M Davidson, Martin Wühr, Matthew G Vander Heiden, Daniel Herranz, Jessie Yanxiang Guo, Yibin Kang, Joshua D Rabinowitz
Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature 614 (7947) (2023)
Rodrigo Romero, Francisco J Sánchez Rivera, Peter M K Westcott, Kim L Mercer, Arjun Bhutkar, Alexander Muir, Tania J González Robles, Swanny Lamboy Rodríguez, Laura Z Liao, Sheng Rong Ng, Leanne Li, Caterina I Colón, Santiago Naranjo, Mary Clare Beytagh, Caroline A Lewis, Peggy P Hsu, Roderick T Bronson, Matthew G Vander Heiden, Tyler Jacks
Publisher Correction: Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1. Nature cancer 1 (9) (2023)
Kevin G Hicks, Ahmad A Cluntun, Heidi L Schubert, Sean R Hackett, Jordan A Berg, Paul G Leonard, Mariana A A Aleixo, Youjia Zhou, Alex J Bott, Sonia R Salvatore, Fei Chang, Aubrie Blevins, Paige Barta, Samantha Tilley, Aaron Leifer, Andrea Guzman, Ajak Arok, Sarah Fogarty, Jacob M Winter, Hee Chul Ahn, Karen N Allen, Samuel Block, Iara Aimê Cardoso, Jianping Ding, Ingrid Dreveny, William C Gasper, Quinn Ho, Atsushi Matsuura, Michael J Palladino, Sabin Prajapati, Pengkai Sun, Kai Tittmann, Dean R Tolan, Judith Unterlass, Andrew P VanDemark, Matthew G Vander Heiden, Bradley A Webb, Cai-Hong Yun, Pengkai Zhao, Bei Wang, Francisco J Schopfer, Christopher P Hill, Maria Cristina Nonato, Florian L Muller, James Eric Cox, Jared Rutter
Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase. Science (New York, N.Y.) 379 (6636) (2023)
Caroline R Bartman, Daniel R Weilandt, Yihui Shen, Won Dong Lee, Yujiao Han, Tara TeSlaa, Connor S R Jankowski, Laith Samarah, Noel R Park, Victoria da Silva-Diz, Maya Aleksandrova, Yetis Gultekin, Argit Marishta, Lin Wang, Lifeng Yang, Asael Roichman, Vrushank Bhatt, Taijin Lan, Zhixian Hu, Xi Xing, Wenyun Lu, Shawn M Davidson, Martin Wühr, Matthew G Vander Heiden, Daniel Herranz, Jessie Yanxiang Guo, Yibin Kang, Joshua D Rabinowitz
Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature (2023)
Christopher S Nabel, Matthew G Vander Heiden
Patient-Derived Xenografts to Study Cancer Metabolism: When Does X Mark the Spot? Cancer research 81 (17) (2022)
Shawn M Davidson, Daniel R Schmidt, Julia E Heyman, James P O'Brien, Amy C Liu, William J Israelsen, Talya L Dayton, Raghav Sehgal, Roderick T Bronson, Elizaveta Freinkman, Howard H Mak, Giuseppe Nicolò Fanelli, Scott Malstrom, Gary Bellinger, Arkaitz Carracedo, Pier Paolo Pandolfi, Kevin Dale Courtney, Abhishek Jha, Ronald A DePinho, James W Horner, Craig J Thomas, Lewis C Cantley, Massimo Loda, Matthew G Vander Heiden
Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma. Cancer research 82 (13) (2022)
Frances F Diehl, Teemu P Miettinen, Ryan Elbashir, Christopher S Nabel, Alicia M Darnell, Brian T Do, Scott R Manalis, Caroline A Lewis, Matthew G Vander Heiden
Nucleotide imbalance decouples cell growth from cell proliferation. Nature cell biology 24 (8) (2022)
Goutam Chakraborty, Subhiksha Nandakumar, Rahim Hirani, Bastien Nguyen, Konrad H Stopsack, Christoph Kreitzer, Sai Harisha Rajanala, Romina Ghale, Ying Z Mazzu, Naga Vara Kishore Pillarsetty, Gwo-Shu Mary Lee, Howard I Scher, Michael J Morris, Tiffany A Traina, Pedram Razavi, Wassim Abida, Jeremy C Durack, Stephen B Solomon, Matthew G Vander Heiden, Lorelei A Mucci, Andreas G Wibmer, Nikolaus Schultz, Philip W Kantoff
The Impact of PIK3R1 Mutations and Insulin-PI3K-Glycolytic Pathway Regulation in Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (16) (2022)
Zhaoqi Li, Brian W Ji, Purushottam D Dixit, Konstantine Tchourine, Evan C Lien, Aaron M Hosios, Keene L Abbott, Justine C Rutter, Anna M Westermark, Elizabeth F Gorodetsky, Lucas B Sullivan, Matthew G Vander Heiden, Dennis Vitkup
Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited. Nature metabolism 4 (6) (2022)
Rupsa Datta, Sharanya Sivanand, Allison N Lau, Logan V Florek, Anna M Barbeau, Jeffrey Wyckoff, Melissa C Skala, Matthew G Vander Heiden
Interactions with stromal cells promote a more oxidized cancer cell redox state in pancreatic tumors. Science advances 8 (3) (2022)
Reuben Franklin, Yiming Guo, Shiyang He, Meijuan Chen, Fei Ji, Xinyue Zhou, David E Frankhouser, Brian T Do, Carmen Chiem, Mihyun Jang, M Andres Blanco, Matthew G Vander Heiden, Russell C Rockne, Maria Ninova, David B Sykes, Konrad Hochedlinger, Rui Lu, Ruslan I Sadreyev, Jernej Murn, Andrew G Volk, Sihem Cheloufi
Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity. Nature communications 13 (1) (2022)
Victoire Gouirand, Tristan Gicquel, Evan C Lien, Emilie Jaune, Quentin Da Costa, Pascal Finetti, Elodie Metay, Camille Duluc, Jared R Mayers, Stephane Audebert, Luc Camoin, Laurence Borge, Marion Rubis, Julie Leca, Véronique Rigot, François Bertucci, Nelson J Dusetti, Juan Lucio Iovanna, Richard Tomasini, Ghislain Bidaut, Fabienne Guillaumond, Matthew G Vander Heiden, Sophie Vasseur
Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression. The EMBO journal 41 (9) (2022)
Xiaoshuang Feng, Cindy Ke Zhou, Andrew T Chan, Kathryn M Wilson, Claire H Pernar, Barbra A Dickerman, Massimo Loda, Stephen P Finn, Kathryn L Penney, Daniel R Schmidt, Matthew G Vander Heiden, Edward L Giovannucci, Ericka M Ebot, Lorelei A Mucci
Association of Prediagnostic Blood Metabolomics with Prostate Cancer Defined by ERG or PTEN Molecular Subtypes. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 30 (5) (2021)
Bradley E Reinfeld, Matthew Z Madden, Melissa M Wolf, Anna Chytil, Jackie E Bader, Andrew R Patterson, Ayaka Sugiura, Allison S Cohen, Ahmed Ali, Brian T Do, Alexander Muir, Caroline A Lewis, Rachel A Hongo, Kirsten L Young, Rachel E Brown, Vera M Todd, Tessa Huffstater, Abin Abraham, Richard T O'Neil, Matthew H Wilson, Fuxue Xin, M Noor Tantawy, W David Merryman, Rachelle W Johnson, Christopher S Williams, Emily F Mason, Frank M Mason, Katherine E Beckermann, Matthew G Vander Heiden, H Charles Manning, Jeffrey C Rathmell, W Kimryn Rathmell
Cell-programmed nutrient partitioning in the tumour microenvironment. Nature 593 (7858) (2021)
Sharanya Sivanand, Matthew G Vander Heiden
Transcriptional activation of macropinocytosis by the Hippo pathway following nutrient limitation. Genes & development 34 (19-20) (2021)
Claire H Pernar, Giovanni Parmigiani, Edward L Giovannucci, Eric B Rimm, Svitlana Tyekucheva, Massimo Loda, Stephen P Finn, Matthew G Vander Heiden, Michelangelo Fiorentino, Ericka M Ebot, Lorelei A Mucci
Gene Expression Pathways in Prostate Tissue Associated with Vigorous Physical Activity in Prostate Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 30 (4) (2021)
Mark A Keibler, Wentao Dong, Keegan D Korthauer, Aaron M Hosios, Sun Jin Moon, Lucas B Sullivan, Nian Liu, Keene L Abbott, Orlando D Arevalo, Kailing Ho, Jennifer Lee, Aasavari S Phanse, Joanne K Kelleher, Othon Iliopoulos, Jonathan L Coloff, Matthew G Vander Heiden, Gregory Stephanopoulos
Differential substrate use in EGF- and oncogenic KRAS-stimulated human mammary epithelial cells. The FEBS journal 288 (19) (2021)
Evan C Lien, Anna M Westermark, Yin Zhang, Chen Yuan, Zhaoqi Li, Allison N Lau, Kiera M Sapp, Brian M Wolpin, Matthew G Vander Heiden
Low glycaemic diets alter lipid metabolism to influence tumour growth. Nature 599 (7884) (2021)
Chenxi Tian, Ying Huang, Karl R Clauser, Steffen Rickelt, Allison N Lau, Steven A Carr, Matthew G Vander Heiden, Richard O Hynes
Suppression of pancreatic ductal adenocarcinoma growth and metastasis by fibrillar collagens produced selectively by tumor cells. Nature communications 12 (1) (2021)
Andrew J Schwartz, Joshua W Goyert, Sumeet Solanki, Samuel Andrew Kerk, Brandon Chen, Cristina Castillo, Peggy P Hsu, Brian T Do, Rashi Singhal, Michael K Dame, Ho-Joon Lee, Jason R Spence, Samira Lakhal-Littleton, Matthew G Vander Heiden, Costas Andreas Lyssiotis, Xiang Xue, Yatrik M Shah
Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells. Nature metabolism 3 (7) (2021)
Mark D Badeaux, Annah S Rolig, Giulia Agnello, Danlee Enzler, Melissa J Kasiewicz, Leslie Priddy, Jason F Wiggins, Alexander Muir, Mark R Sullivan, Jessica Van Cleef, Christopher Daige, Matthew G Vander Heiden, Venkatesh Rajamanickam, James E Wooldridge, William L Redmond, Scott W Rowlinson
Arginase Therapy Combines Effectively with Immune Checkpoint Blockade or Agonist Anti-OX40 Immunotherapy to Control Tumor Growth. Cancer immunology research 9 (4) (2021)
Mark R Sullivan, Alicia M Darnell, Montana F Reilly, Tenzin Kunchok, Lena Joesch-Cohen, Daniel Rosenberg, Ahmed Ali, Matthew G Rees, Jennifer A Roth, Caroline A Lewis, Matthew G Vander Heiden
Methionine synthase is essential for cancer cell proliferation in physiological folate environments. Nature metabolism 3 (11) (2021)
Leanne Li, Sheng Rong Ng, Caterina I Colón, Benjamin J Drapkin, Peggy P Hsu, Zhaoqi Li, Christopher S Nabel, Caroline A Lewis, Rodrigo Romero, Kim L Mercer, Arjun Bhutkar, Sarah Phat, David T Myers, Mandar Deepak Muzumdar, Peter M K Westcott, Mary Clare Beytagh, Anna F Farago, Matthew G Vander Heiden, Nicholas J Dyson, Tyler Jacks
Identification of DHODH as a therapeutic target in small cell lung cancer. Science translational medicine 11 (517) (2020)
Bryan Ngo, Eugenie Kim, Victoria Osorio-Vasquez, Sophia Doll, Sophia Bustraan, Roger J Liang, Alba Luengo, Shawn M Davidson, Ahmed Ali, Gino B Ferraro, Grant M Fischer, Roozbeh Eskandari, Diane S Kang, Jing Ni, Ariana Plasger, Vinagolu K Rajasekhar, Edward R Kastenhuber, Sarah Bacha, Roshan K Sriram, Benjamin D Stein, Samuel F Bakhoum, Matija Snuderl, Paolo Cotzia, John H Healey, Nello Mainolfi, Vipin Suri, Adam Friedman, Mark Manfredi, David M Sabatini, Drew R Jones, Min Yu, Jean J Zhao, Rakesh K Jain, Kayvan R Keshari, Michael A Davies, Matthew G Vander Heiden, Eva Hernando, Matthias Mann, Lewis C Cantley, Michael E Pacold
Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition. Cancer discovery 10 (9) (2020)
Allison N Lau, Zhaoqi Li, Laura V Danai, Anna M Westermark, Alicia M Darnell, Raphael Ferreira, Vasilena Gocheva, Sharanya Sivanand, Evan C Lien, Kiera M Sapp, Jared R Mayers, Giulia Biffi, Christopher R Chin, Shawn M Davidson, David A Tuveson, Tyler Jacks, Nicholas J Matheson, Omer Yilmaz, Matthew G Vander Heiden
Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma. eLife 9 (2020)
Nimrat Chatterjee, Matthew A Whitman, Cynthia A Harris, Sophia M Min, Oliver Jonas, Evan C Lien, Alba Luengo, Matthew G Vander Heiden, Jiyong Hong, Pei Zhou, Michael T Hemann, Graham C Walker
REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks. Proceedings of the National Academy of Sciences of the United States of America 117 (46) (2020)
Ralph Francescone, Debora Barbosa Vendramini-Costa, Janusz Franco-Barraza, Jessica Wagner, Alexander Muir, Allison N Lau, Linara Gabitova, Tatiana Pazina, Sapna Gupta, Tiffany Luong, Dustin Rollins, Ruchi Malik, Roshan J Thapa, Diana Restifo, Yan Zhou, Kathy Q Cai, Harvey H Hensley, Yinfei Tan, Warren D Kruger, Karthik Devarajan, Siddharth Balachandran, Andres J Klein-Szanto, Huamin Wang, Wafik S El-Deiry, Matthew G Vander Heiden, Suraj Peri, Kerry S Campbell, Igor Astsaturov, Edna Cukierman
Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast-Driven Nutritional Support and Immunosuppression. Cancer discovery 11 (2) (2020)
Barbra A Dickerman, Ericka M Ebot, Brian C Healy, Kathryn M Wilson, A Heather Eliassen, Alberto Ascherio, Claire H Pernar, Oana A Zeleznik, Matthew G Vander Heiden, Clary B Clish, Edward Giovannucci, Lorelei A Mucci
A Metabolomics Analysis of Adiposity and Advanced Prostate Cancer Risk in the Health Professionals Follow-Up Study. Metabolites 10 (3) (2020)
Yingzhong Li, Nikola A Ivica, Ting Dong, Dimitrios P Papageorgiou, Yanpu He, Douglas R Brown, Marianna Kleyman, Guangan Hu, Walter W Chen, Lucas B Sullivan, Amanda Del Rosario, Paula T Hammond, Matthew G Vander Heiden, Jianzhu Chen
MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme. Nature communications 11 (1) (2020)
Xin Jin, Zelalem Demere, Karthik Nair, Ahmed Ali, Gino B Ferraro, Ted Natoli, Amy Deik, Lia Petronio, Andrew A Tang, Cong Zhu, Li Wang, Danny Rosenberg, Vamsi Mangena, Jennifer Roth, Kwanghun Chung, Rakesh K Jain, Andrew T Chan, Matthew G Vander Heiden, Todd R Golub
A metastasis map of human cancer cell lines. Nature 588 (7837) (2020)
Joon Ho Kang, Georgios Katsikis, Zhaoqi Li, Kiera M Sapp, Max A Stockslager, Daniel Lim, Matthew G Vander Heiden, Micheal B Yaffe, Scott R Manalis, Teemu P Miettinen
Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis during cell division. Nature communications 11 (1) (2020)
Ana Babic, Michael H Rosenthal, William R Bamlet, Naoki Takahashi, Motokazu Sugimoto, Laura V Danai, Vicente Morales-Oyarvide, Natalia Khalaf, Richard F Dunne, Lauren K Brais, Marisa W Welch, Caitlin L Zellers, Courtney Dennis, Nader Rifai, Carla M Prado, Bette Caan, Tilak K Sundaresan, Jeffrey A Meyerhardt, Matthew H Kulke, Clary B Clish, Kimmie Ng, Matthew G Vander Heiden, Gloria M Petersen, Brian M Wolpin
Postdiagnosis Loss of Skeletal Muscle, but Not Adipose Tissue, Is Associated with Shorter Survival of Patients with Advanced Pancreatic Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 28 (12) (2019)

Matthew G Vander Heiden.css-eqlu8i{font-size:small;padding-left:4px;} (Matthew Vander Heiden)

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Matthew G Vander Heiden (Matthew Vander Heiden)