Complement 3a Mediates CCN2/CTGF in Human Retinal Pigment Epithelial Cells.

Guang-Ming WanZhiyan XuZhengyu ChenQin Long You-Xin Chen

Published in: Journal of ophthalmology (2022)

C3 was elevated in RPE under environmental stimulus and long-term exposure to specified concentration of C3a increased CCN2/CTGF expression in RPE, which could be partially reversed by C3 siRNA.

Keyphrases

endothelial cells
poor prognosis
induced pluripotent stem cells
pluripotent stem cells
binding protein
hyaluronic acid
drug delivery
climate change
life cycle