Resveratrol treatment alleviated pathologies and downregulated NFκB expression in hippocampus. TBI caused adverse alterations in free radicals' balance system and histological structures of hippocampus. Resveratrol with its antioxidant and anti-inflammatory effects reduced the damage caused by TBI.
Keyphrases
- signaling pathway
- anti inflammatory
- oxidative stress
- traumatic brain injury
- lps induced
- prefrontal cortex
- cerebral ischemia
- cognitive impairment
- pi k akt
- poor prognosis
- nuclear factor
- severe traumatic brain injury
- mild traumatic brain injury
- high resolution
- inflammatory response
- emergency department
- long non coding rna
- binding protein
- adverse drug