Analgesic Efficacy of Intravenous Ibuprofen in the Treatment of Postoperative Acute Pain: A Phase III Multicenter Randomized Placebo-ControlledDouble-Blind Clinical Trial.
Hong-Su ZhouTing-Ting LiYu PiTing-Hua WangYunxia ZuoLiu-Lin XiongPublished in: Pain research & management (2023)
Intermittent IV administration of ibuprofen 400 mg or 800 mg within 24 h after surgery in patients undergoing abdominal and orthopedic surgery significantly decreased morphine consumption and relieved pain, without increasing the incidence of AEs.
Keyphrases
- phase iii
- double blind
- clinical trial
- patients undergoing
- open label
- placebo controlled
- neuropathic pain
- chronic pain
- phase ii
- pain management
- postoperative pain
- minimally invasive
- liver failure
- risk factors
- spinal cord
- study protocol
- coronary artery bypass
- high dose
- randomized controlled trial
- high intensity
- spinal cord injury
- anti inflammatory
- aortic dissection
- cross sectional
- surgical site infection
- hepatitis b virus
- acute coronary syndrome