A Repeated Measures Pilot Comparison of Trajectories of Fluctuating Endogenous Hormones in Young Women with Traumatic Brain Injury, Healthy Controls.
Janet P NiemeierPaul B PerrinBradley S HurstDavid M FoureauToan T HuynhSusan L EvansJonathan E SilvermanM Elise McClannahanBenjamin D BruschMark NewmanJean-Luc MougeotAmy K WagnerPublished in: Behavioural neurology (2019)
Acute TBI may suppress E2 and increase CORT in young women. OCs appeared to independently affect CORT and FSH responses. Future work is needed with a larger sample to characterize TBI effects on women's endogenous hormone response to injury and OC use's effects on post-TBI stress response and gonadal function, as well as secondary injury.
Keyphrases
- traumatic brain injury
- severe traumatic brain injury
- liver failure
- polycystic ovary syndrome
- depressive symptoms
- current status
- respiratory failure
- drug induced
- study protocol
- middle aged
- mild traumatic brain injury
- pregnancy outcomes
- randomized controlled trial
- type diabetes
- adipose tissue
- metabolic syndrome
- intensive care unit
- hepatitis b virus
- pregnant women
- breast cancer risk
- extracorporeal membrane oxygenation
- mechanical ventilation