MutationalPatterns: the one stop shop for the analysis of mutational processes.
Freek MandersArianne M BrandsmaJurrian K de KanterMark VerheulRurika OkaMarkus J van RoosmalenBastiaan R Van der RoestArne Van HoeckEdwin CuppenRuben van BoxtelPublished in: BMC genomics (2022)
This novel version of MutationalPatterns allows for more comprehensive analyses and visualization of mutational patterns in order to study the underlying processes. Ultimately, in-depth mutational analyses may contribute to improved biological insights in mechanisms of mutation accumulation as well as aid cancer diagnostics. MutationalPatterns is freely available at http://bioconductor.org/packages/MutationalPatterns .