Edwin Cuppen (E Cuppen)

ORCID

Publication Activity (10 Years)

Years Active: 2013-2024
Publications (10 Years): 55

Top Venues

Nature genetics

Nature communications

Science (New York, N.Y.)

JCO precision oncology

This page only lists publications with an associated author ORCID identifier.

Publications

Michela Riba, Cinzia Felicita Sala, Aedin C Culhane, Åsmund Flobak, Attila Patocs, Kjetil Boye, Karla Plevova, Sarka Pospisilova, Giorgia Gandolfi, Marco J Morelli, Gabriele Bucci, Anders Edsjö, Ulrik N Lassen, Fátima Al-Shahrour, Núria López-Bigas, Randi Hovland, Edwin Cuppen, Alfonso Valencia, Helene A Poirel, Richard Rosenquist, Serena Scollen, Juan Arenas Marquez, Jeroen A M Beliën, Arcangela De Nicolo, Ruggero De Maria, David Torrents, Giovanni Tonon
The 1+Million Genomes Minimal Dataset for Cancer. Nature genetics 56 (5) (2024)
Michela Riba, Cinzia Felicita Sala, Aedin C Culhane, Åsmund Flobak, Attila Patocs, Kjetil Boye, Karla Plevova, Sarka Pospisilova, Giorgia Gandolfi, Marco J Morelli, Gabriele Bucci, Anders Edsjö, Ulrik N Lassen, Fátima Al-Shahrour, Núria López-Bigas, Randi Hovland, Edwin Cuppen, Alfonso Valencia, Helene A Poirel, Richard Rosenquist, Serena Scollen, Juan Arenas Marquez, Jeroen A M Beliën, Arcangela De Nicolo, Ruggero De Maria, David Torrents, Giovanni Tonon
The 1+Million Genomes Minimal Dataset for Cancer. Nature genetics 56 (5) (2024)
Mira C Hasner, Mark P van Opijnen, Filip Yves Francine De Vos, Edwin Cuppen, Marike L D Broekman
Whole genome sequencing in (recurrent) glioblastoma: challenges related to informed consent procedures and data sharing. Acta neurochirurgica 166 (1) (2024)
Mira C Hasner, Mark P van Opijnen, Filip Yves Francine De Vos, Edwin Cuppen, Marike L D Broekman
Whole genome sequencing in (recurrent) glioblastoma: challenges related to informed consent procedures and data sharing. Acta neurochirurgica 166 (1) (2024)
Joris van de Haar, Joanne M Mankor, Karlijn Hummelink, Kim Monkhorst, Egbert F Smit, Lodewyk F A Wessels, Edwin Cuppen, Joachim G J V Aerts, Emile E Voest
Combining Genomic Biomarkers to Guide Immunotherapy in Non-Small Cell Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (7) (2024)
Joseph Usset, Axel Rosendahl Huber, Maria A Andrianova, Eduard Batlle, Joan Carles, Edwin Cuppen, Elena Elez, Enriqueta Felip, Marina Gómez-Rey, Deborah Lo Giacco, Francisco Martinez-Jimenez, Eva Muñoz Couselo, Lillian L Siu, Josep Tabernero, Ana Vivancos, Ferran Muinos, Nuria Lopez-Bigas, Núria López-Bigas
Five latent factors underlie response to immunotherapy. Nature genetics (2024)
Michela Riba, Cinzia Felicita Sala, Aedin C Culhane, Åsmund Flobak, Attila Patocs, Kjetil Boye, Karla Plevova, Sarka Pospisilova, Giorgia Gandolfi, Marco J Morelli, Gabriele Bucci, Anders Edsjö, Ulrik N Lassen, Fátima Al-Shahrour, Núria López-Bigas, Randi Hovland, Edwin Cuppen, Alfonso Valencia, Helene A Poirel, Richard Rosenquist, Serena Scollen, Juan Arenas Marquez, Jeroen A M Beliën, Arcangela De Nicolo, Ruggero De Maria, David Torrents, Giovanni Tonon
The 1+Million Genomes Minimal Dataset for Cancer. Nature genetics (2024)
Mira C Hasner, Mark P van Opijnen, Filip Yves Francine De Vos, Edwin Cuppen, Marike L D Broekman
Whole genome sequencing in (recurrent) glioblastoma: challenges related to informed consent procedures and data sharing. Acta neurochirurgica 166 (1) (2024)
Joris van de Haar, Joanne M Mankor, Karlijn Hummelink, Kim Monkhorst, Egbert F Smit, Lodewyk F A Wessels, Edwin Cuppen, Joachim G J V Aerts, Emile E Voest
Combining genomic biomarkers to guide immunotherapy in non-small cell lung cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Francisco Martinez-Jimenez, Ali Movasati, Sascha Remy Brunner, Luan Nguyen, Peter Priestley, Edwin Cuppen, Arne Van Hoeck
Pan-cancer whole-genome comparison of primary and metastatic solid tumours. Nature (2023)
Francisco Martinez-Jimenez, Ali Movasati, Sascha Remy Brunner, Luan Nguyen, Peter Priestley, Edwin Cuppen, Arne Van Hoeck
Pan-cancer whole-genome comparison of primary and metastatic solid tumours. Nature (2023)
Mandy L Ballinger, Swetansu Pattnaik, Piyushkumar A Mundra, Milita Zaheed, Emma M Rath, Peter Priestley, Jonathan Baber, Isabelle L Ray-Coquard, Nicholas Isambert, Sylvain Causeret, Winette T A van der Graaf, Ajay Puri, Florence Duffaud, Axel Le Cesne, Beatrice Seddon, Coonoor Chandrasekar, Joshua D Schiffman, Andrew S Brohl, Paul A James, Jean-Emmanuel Kurtz, Nicolas Penel, Ola Myklebost, Leonardo A Meza-Zepeda, Hilda Pickett, Maya Kansara, Nicola Waddell, Olga Kondrashova, John V Pearson, Andrew P Barbour, Sherly X Li, Tuong Linh Nguyen, Diane Fatkin, Robert M Graham, Eleni Giannoulatou, Melissa Jane Green, Warren Kaplan, Shyamsundar Ravishankar, Joseph Copty, Joseph E Powell, Edwin Cuppen, Kristel van Eijk, Jan Herman Veldink, Jin-Hee Ahn, Jeong Eun Kim, Robert Lor Randall, Katherine M Tucker, Ian R Judson, Rajiv Sarin, Thomas E Ludwig, French Exome Consortium, Jean François Deleuze, null null, Michelle Haber, Glenn M Marshall, Murray J Cairns, Jean Yves Blay, null null, David M Thomas, Martin Tattersall, Susan Neuhaus, Craig Lewis, Kathy Tucker, Richard Carey-Smith, David Wood, Sandro Porceddu, Ian Dickinson, Heather Thorne, Paul James, Isabelle Ray-Coquard, Jean-Yves Blay, Philippe Cassier, Axel Le Cesne, Florence Duffaud, Nicolas Penel, Nicolas Isambert, Jean-Emmanuel Kurtz, Ajay Puri, Rajiv Sarin, Jin-Hee Ahn, Jeong Eun Kim, Iain Ward, Ian Judson, Winette van der Graaf, Beatrice Seddon, Coonoor Chandrasekar, Rory Rickar, Ivo Hennig, Joshua Schiffman, R Lor Randall, Audrey Silvestri, Anaiis Zaratzian, Michael Tayao, Kelly Walwyn, Eveline Niedermayr, Denia Mang, Richard Clark, Tina Thorpe, Jessica MacDonald, Kim Riddell, Jasmine Mar, Vicki Fennelly, Allison Wicht, Belinda Zielony, Emma Galligan, Genna Glavich, Johanna Stoeckert, Lynda Williams, Lana Djandjgava, Iwona Buettner, Carla Osinki, Sonya Stephens, Muriel Rogasik, Laure Bouclier, Magali Girodet, Amandine Charreton, Yohan Fayet, Saniya Crasto, Bhanupriya Sandupatla, Yeon Yoon, Noda Je, Liz Thompson, Trent Fowler, Bella Johnson, Galina Petrikova, Thomas Hambridge, Angela Hutchins, Diego Bottero, Deborah Scanlon, Jo Stokes-Denson, Emmanuelle Génin, Dominique Campion, Jean-François Dartigues, Jean-François Deleuze, Jean-Charles Lambert, Richard Redon, Thomas Ludwig, Benjamin Grenier-Boley, Sébastien Letort, Pierre Lindenbaum, Vincent Meyer, Olivier Quenez, Christian Dina, Céline Bellenguez, Camille Charbonnier Le Clézio, Joanna Giemza, Stéphanie Chatel, Claude Férec, Hervé Le Marec, Luc Letenneur, Gaël Nicolas, Karen Rouault
Heritable defects in telomere and mitotic function selectively predispose to sarcomas. Science (New York, N.Y.) 379 (6629) (2023)
Francisco Martinez-Jimenez, Peter Priestley, Charles Shale, Jonathan Baber, Erik Rozemuller, Edwin Cuppen
Genetic immune escape landscape in primary and metastatic cancer. Nature genetics 55 (5) (2023)
Francisco Martinez-Jimenez, Peter Priestley, Charles Shale, Jonathan Baber, Erik Rozemuller, Edwin Cuppen
Genetic immune escape landscape in primary and metastatic cancer. Nature genetics 55 (5) (2023)
B van de Kooij, A Schreuder, Raphael S Pavani, V Garzero, Arne Van Hoeck, Marta San Martin Alonso, D Koerse, T J Wendel, E Callen, J Boom, Hailiang Mei, Edwin Cuppen, A Nussenzweig, Haico van Attikum, Sylvie M Noordermeer
EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells. bioRxiv : the preprint server for biology (2023)
Kris G Samsom, Linda J W Bosch, Luuk J Schipper, Daoin Schout, Paul Roepman, Mirjam C Boelens, Ferry Lalezari, Elisabeth G Klompenhouwer, Adrianus J de Langen, Tineke E Buffart, Berit M H van Linder, Kelly van Deventer, Kay van den Burg, Unga Unmehopa, Efraim H Rosenberg, Roelof Koster, Frans B L Hogervorst, José G van den Berg, Immy Riethorst, Lieke Schoenmaker, Daphne van Beek, Ewart de Bruijn, Jacobus J M van der Hoeven, Hans van Snellenberg, Lizet E van der Kolk, Edwin Cuppen, Emile E Voest, Gerrit A Meijer, Kim Monkhorst
Optimized whole-genome sequencing workflow for tumor diagnostics in routine pathology practice. Nature protocols (2023)
Francisco Martinez-Jimenez, Peter Priestley, Charles Shale, Jonathan Baber, Erik Rozemuller, Edwin Cuppen
Genetic immune escape landscape in primary and metastatic cancer. Nature genetics 55 (5) (2023)
Mandy L Ballinger, Swetansu Pattnaik, Piyushkumar A Mundra, Milita Zaheed, Emma M Rath, Peter Priestley, Jonathan Baber, Isabelle L Ray-Coquard, Nicholas Isambert, Sylvain Causeret, Winette T A van der Graaf, Ajay Puri, Florence Duffaud, Axel Le Cesne, Beatrice Seddon, Coonoor Chandrasekar, Joshua D Schiffman, Andrew S Brohl, Paul A James, Jean-Emmanuel Kurtz, Nicolas Penel, Ola Myklebost, Leonardo A Meza-Zepeda, Hilda Pickett, Maya Kansara, Nicola Waddell, Olga Kondrashova, John V Pearson, Andrew P Barbour, Sherly X Li, Tuong Linh Nguyen, Diane Fatkin, Robert M Graham, Eleni Giannoulatou, Melissa Jane Green, Warren Kaplan, Shyamsundar Ravishankar, Joseph Copty, Joseph E Powell, Edwin Cuppen, Kristel van Eijk, Jan Herman Veldink, Jin-Hee Ahn, Jeong Eun Kim, Robert Lor Randall, Katherine M Tucker, Ian R Judson, Rajiv Sarin, Thomas E Ludwig, French Exome Consortium, Jean François Deleuze, null null, Michelle Haber, Glenn M Marshall, Murray J Cairns, Jean Yves Blay, null null, David M Thomas, Martin Tattersall, Susan Neuhaus, Craig Lewis, Kathy Tucker, Richard Carey-Smith, David Wood, Sandro Porceddu, Ian Dickinson, Heather Thorne, Paul James, Isabelle Ray-Coquard, Jean-Yves Blay, Philippe Cassier, Axel Le Cesne, Florence Duffaud, Nicolas Penel, Nicolas Isambert, Jean-Emmanuel Kurtz, Ajay Puri, Rajiv Sarin, Jin-Hee Ahn, Jeong Eun Kim, Iain Ward, Ian Judson, Winette van der Graaf, Beatrice Seddon, Coonoor Chandrasekar, Rory Rickar, Ivo Hennig, Joshua Schiffman, R Lor Randall, Audrey Silvestri, Anaiis Zaratzian, Michael Tayao, Kelly Walwyn, Eveline Niedermayr, Denia Mang, Richard Clark, Tina Thorpe, Jessica MacDonald, Kim Riddell, Jasmine Mar, Vicki Fennelly, Allison Wicht, Belinda Zielony, Emma Galligan, Genna Glavich, Johanna Stoeckert, Lynda Williams, Lana Djandjgava, Iwona Buettner, Carla Osinki, Sonya Stephens, Muriel Rogasik, Laure Bouclier, Magali Girodet, Amandine Charreton, Yohan Fayet, Saniya Crasto, Bhanupriya Sandupatla, Yeon Yoon, Noda Je, Liz Thompson, Trent Fowler, Bella Johnson, Galina Petrikova, Thomas Hambridge, Angela Hutchins, Diego Bottero, Deborah Scanlon, Jo Stokes-Denson, Emmanuelle Génin, Dominique Campion, Jean-François Dartigues, Jean-François Deleuze, Jean-Charles Lambert, Richard Redon, Thomas Ludwig, Benjamin Grenier-Boley, Sébastien Letort, Pierre Lindenbaum, Vincent Meyer, Olivier Quenez, Christian Dina, Céline Bellenguez, Camille Charbonnier Le Clézio, Joanna Giemza, Stéphanie Chatel, Claude Férec, Hervé Le Marec, Luc Letenneur, Gaël Nicolas, Karen Rouault
Heritable defects in telomere and mitotic function selectively predispose to sarcomas. Science (New York, N.Y.) 379 (6629) (2023)
Francisco Martinez-Jimenez, Peter Priestley, Charles Shale, Jonathan Baber, Erik Rozemuller, Edwin Cuppen
Genetic immune escape landscape in primary and metastatic cancer. Nature genetics 55 (5) (2023)
Mandy L Ballinger, Swetansu Pattnaik, Piyushkumar A Mundra, Milita Zaheed, Emma M Rath, Peter Priestley, Jonathan Baber, Isabelle L Ray-Coquard, Nicholas Isambert, Sylvain Causeret, Winette T A van der Graaf, Ajay Puri, Florence Duffaud, Axel Le Cesne, Beatrice Seddon, Coonoor Chandrasekar, Joshua D Schiffman, Andrew S Brohl, Paul A James, Jean-Emmanuel Kurtz, Nicolas Penel, Ola Myklebost, Leonardo A Meza-Zepeda, Hilda Pickett, Maya Kansara, Nicola Waddell, Olga Kondrashova, John V Pearson, Andrew P Barbour, Sherly X Li, Tuong Linh Nguyen, Diane Fatkin, Robert M Graham, Eleni Giannoulatou, Melissa Jane Green, Warren Kaplan, Shyamsundar Ravishankar, Joseph Copty, Joseph E Powell, Edwin Cuppen, Kristel van Eijk, Jan Herman Veldink, Jin-Hee Ahn, Jeong Eun Kim, Robert Lor Randall, Katherine M Tucker, Ian R Judson, Rajiv Sarin, Thomas E Ludwig, French Exome Consortium, Jean François Deleuze, null null, Michelle Haber, Glenn M Marshall, Murray J Cairns, Jean Yves Blay, null null, David M Thomas, Martin Tattersall, Susan Neuhaus, Craig Lewis, Kathy Tucker, Richard Carey-Smith, David Wood, Sandro Porceddu, Ian Dickinson, Heather Thorne, Paul James, Isabelle Ray-Coquard, Jean-Yves Blay, Philippe Cassier, Axel Le Cesne, Florence Duffaud, Nicolas Penel, Nicolas Isambert, Jean-Emmanuel Kurtz, Ajay Puri, Rajiv Sarin, Jin-Hee Ahn, Jeong Eun Kim, Iain Ward, Ian Judson, Winette van der Graaf, Beatrice Seddon, Coonoor Chandrasekar, Rory Rickar, Ivo Hennig, Joshua Schiffman, R Lor Randall, Audrey Silvestri, Anaiis Zaratzian, Michael Tayao, Kelly Walwyn, Eveline Niedermayr, Denia Mang, Richard Clark, Tina Thorpe, Jessica MacDonald, Kim Riddell, Jasmine Mar, Vicki Fennelly, Allison Wicht, Belinda Zielony, Emma Galligan, Genna Glavich, Johanna Stoeckert, Lynda Williams, Lana Djandjgava, Iwona Buettner, Carla Osinki, Sonya Stephens, Muriel Rogasik, Laure Bouclier, Magali Girodet, Amandine Charreton, Yohan Fayet, Saniya Crasto, Bhanupriya Sandupatla, Yeon Yoon, Noda Je, Liz Thompson, Trent Fowler, Bella Johnson, Galina Petrikova, Thomas Hambridge, Angela Hutchins, Diego Bottero, Deborah Scanlon, Jo Stokes-Denson, Emmanuelle Génin, Dominique Campion, Jean-François Dartigues, Jean-François Deleuze, Jean-Charles Lambert, Richard Redon, Thomas Ludwig, Benjamin Grenier-Boley, Sébastien Letort, Pierre Lindenbaum, Vincent Meyer, Olivier Quenez, Christian Dina, Céline Bellenguez, Camille Charbonnier Le Clézio, Joanna Giemza, Stéphanie Chatel, Claude Férec, Hervé Le Marec, Luc Letenneur, Gaël Nicolas, Karen Rouault
Heritable defects in telomere and mitotic function selectively predispose to sarcomas. Science (New York, N.Y.) 379 (6629) (2023)
Mandy L Ballinger, Swetansu Pattnaik, Piyushkumar A Mundra, Milita Zaheed, Emma M Rath, Peter Priestley, Jonathan Baber, Isabelle L Ray-Coquard, Nicholas Isambert, Sylvain Causeret, Winette T A van der Graaf, Ajay Puri, Florence Duffaud, Axel Le Cesne, Beatrice Seddon, Coonoor Chandrasekar, Joshua D Schiffman, Andrew S Brohl, Paul A James, Jean-Emmanuel Kurtz, Nicolas Penel, Ola Myklebost, Leonardo A Meza-Zepeda, Hilda Pickett, Maya Kansara, Nicola Waddell, Olga Kondrashova, John V Pearson, Andrew P Barbour, Sherly X Li, Tuong Linh Nguyen, Diane Fatkin, Robert M Graham, Eleni Giannoulatou, Melissa Jane Green, Warren Kaplan, Shyamsundar Ravishankar, Joseph Copty, Joseph E Powell, Edwin Cuppen, Kristel van Eijk, Jan Herman Veldink, Jin-Hee Ahn, Jeong Eun Kim, Robert Lor Randall, Katherine M Tucker, Ian R Judson, Rajiv Sarin, Thomas E Ludwig, French Exome Consortium, Jean François Deleuze, null null, Michelle Haber, Glenn M Marshall, Murray J Cairns, Jean Yves Blay, null null, David M Thomas, Martin Tattersall, Susan Neuhaus, Craig Lewis, Kathy Tucker, Richard Carey-Smith, David Wood, Sandro Porceddu, Ian Dickinson, Heather Thorne, Paul James, Isabelle Ray-Coquard, Jean-Yves Blay, Philippe Cassier, Axel Le Cesne, Florence Duffaud, Nicolas Penel, Nicolas Isambert, Jean-Emmanuel Kurtz, Ajay Puri, Rajiv Sarin, Jin-Hee Ahn, Jeong Eun Kim, Iain Ward, Ian Judson, Winette van der Graaf, Beatrice Seddon, Coonoor Chandrasekar, Rory Rickar, Ivo Hennig, Joshua Schiffman, R Lor Randall, Audrey Silvestri, Anaiis Zaratzian, Michael Tayao, Kelly Walwyn, Eveline Niedermayr, Denia Mang, Richard Clark, Tina Thorpe, Jessica MacDonald, Kim Riddell, Jasmine Mar, Vicki Fennelly, Allison Wicht, Belinda Zielony, Emma Galligan, Genna Glavich, Johanna Stoeckert, Lynda Williams, Lana Djandjgava, Iwona Buettner, Carla Osinki, Sonya Stephens, Muriel Rogasik, Laure Bouclier, Magali Girodet, Amandine Charreton, Yohan Fayet, Saniya Crasto, Bhanupriya Sandupatla, Yeon Yoon, Noda Je, Liz Thompson, Trent Fowler, Bella Johnson, Galina Petrikova, Thomas Hambridge, Angela Hutchins, Diego Bottero, Deborah Scanlon, Jo Stokes-Denson, Emmanuelle Génin, Dominique Campion, Jean-François Dartigues, Jean-François Deleuze, Jean-Charles Lambert, Richard Redon, Thomas Ludwig, Benjamin Grenier-Boley, Sébastien Letort, Pierre Lindenbaum, Vincent Meyer, Olivier Quenez, Christian Dina, Céline Bellenguez, Camille Charbonnier Le Clézio, Joanna Giemza, Stéphanie Chatel, Claude Férec, Hervé Le Marec, Luc Letenneur, Gaël Nicolas, Karen Rouault
Heritable defects in telomere and mitotic function selectively predispose to sarcomas. Science (New York, N.Y.) 379 (6629) (2023)
Francisco Martinez-Jimenez, Peter Priestley, Charles Shale, Jonathan Baber, Erik Rozemuller, Edwin Cuppen
Genetic immune escape landscape in primary and metastatic cancer. Nature genetics (2023)
Lindsay Angus, Marcel Smid, Saskia M Wilting, Manouk K Bos, Neeltje Steeghs, Inge R H M Konings, Vivianne C G Tjan-Heijnen, Johanna M G H van Riel, Agnes J van de Wouw, null Cpct Consortium, Edwin Cuppen, Martijn Paul Lolkema, Agnes Jager, Stefan Sleijfer, John W M Martens
Genomic Alterations Associated with Estrogen Receptor Pathway Activity in Metastatic Breast Cancer Have a Differential Impact on Downstream ER Signaling. Cancers 15 (17) (2023)
Felix Dietlein, Alex B Wang, Christian Fagre, Anran Tang, Nicolle J M Besselink, Edwin Cuppen, Chunliang Li, Shamil R Sunyaev, James T Neal, Eliezer Van Allen
Genome-wide analysis of somatic noncoding mutation patterns in cancer. Science (New York, N.Y.) 376 (6589) (2022)
Chris J de Witte, Joachim Kutzera, Arne van Hoeck, Luan Nguyen, Ingrid A Boere, Mathilde Jalving, Petronella B Ottevanger, Christa van Schaik-van de Mheen, Marion A Stevense-den Boer, Wigard P Kloosterman, Ronald P Zweemer, Edwin Cuppen, Petronella O Witteveen
Distinct Genomic Profiles Are Associated with Treatment Response and Survival in Ovarian Cancer. Cancers 14 (6) (2022)
Edwin Cuppen, Olivier Elemento, Richard Rosenquist, Svetlana Nikic, Maarten IJzerman, Isabelle Durand Zaleski, Geert Frederix, Lars-Åke Levin, Charles G Mullighan, Reinhard Buttner, Trevor J Pugh, Sean M Grimmond, Carlos Caldas, Fabrice Andre, Ilse Custers, Elias Campo, Hans van Snellenberg, Anna Schuh, Hidewaki Nakagawa, Christof von Kalle, Torsten Haferlach, Stefan Fröhling, Vaidehi Jobanputra
Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care. JCO precision oncology 6 (2022)
Maria Vougioukalaki, Joris Demmers, Wilbert P Vermeij, Marjolein Baar, Serena Bruens, Aristea Magaraki, Ewart W Kuijk, Myrthe Jager, Sarra Merzouk, Renata M C Brandt, Janneke Kouwenberg, Ruben van Boxtel, Edwin Cuppen, Joris Pothof, Jan H J Hoeijmakers
Different responses to DNA damage determine ageing differences between organs. Aging cell 21 (4) (2022)
Luan Nguyen, Arne Van Hoeck, Edwin Cuppen
Machine learning-based tissue of origin classification for cancer of unknown primary diagnostics using genome-wide mutation features. Nature communications 13 (1) (2022)
Edwin Cuppen, Olivier Elemento, Richard Rosenquist, Svetlana Nikic, Maarten IJzerman, Isabelle Durand Zaleski, Geert Frederix, Lars-Åke Levin, Charles G Mullighan, Reinhard Buttner, Trevor J Pugh, Sean M Grimmond, Carlos Caldas, Fabrice Andre, Ilse Custers, Elias Campo, Hans van Snellenberg, Anna Schuh, Hidewaki Nakagawa, Christof von Kalle, Torsten Haferlach, Stefan Fröhling, Vaidehi Jobanputra
Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care. JCO precision oncology 6 (2022)
Freek Manders, Arianne M Brandsma, Jurrian K de Kanter, Mark Verheul, Rurika Oka, Markus J van Roosmalen, Bastiaan R Van der Roest, Arne Van Hoeck, Edwin Cuppen, Ruben van Boxtel
MutationalPatterns: the one stop shop for the analysis of mutational processes. BMC genomics 23 (1) (2022)
Ewart W Kuijk, Onno W Kranenburg, Edwin Cuppen, Arne Van Hoeck
Common anti-cancer therapies induce somatic mutations in stem cells of healthy tissue. Nature communications 13 (1) (2022)
Louisa R Hoes, J Maxime van Berge Henegouwen, Hanneke van der Wijngaart, Laurien J Zeverijn, Daphne L van der Velden, Joris van de Haar, Paul Roepman, Wendy W J de Leng, Anne M L Jansen, Erik D van Werkhoven, Vincent van den Noort, Alwin D R Huitema, Eelke H Gort, Jan Willem B de Groot, Emile D Kerver, Derk-Jan A de Groot, Frans Erdkamp, Laurens V Beerepoot, Marieke H J van den Beuken-van Everdingen, Egbert F Smit, Winette T A van der Graaf, Carla M L van Herpen, Mariette Labots, Ann Hoeben, Hans Morreau, Martijn Paul Lolkema, Edwin Cuppen, André B P van Kuilenburg, Henk M W Verheul, Emile E Voest
Patients with Rare Cancers in the Drug Rediscovery Protocol (DRUP) Benefit from Genomics-Guided Treatment. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (7) (2022)
Edwin Cuppen, Olivier Elemento, Richard Rosenquist, Svetlana Nikic, Maarten IJzerman, Isabelle Durand Zaleski, Geert Frederix, Lars-Åke Levin, Charles G Mullighan, Reinhard Buttner, Trevor J Pugh, Sean M Grimmond, Carlos Caldas, Fabrice Andre, Ilse Custers, Elias Campo, Hans van Snellenberg, Anna Schuh, Hidewaki Nakagawa, Christof von Kalle, Torsten Haferlach, Stefan Fröhling, Vaidehi Jobanputra
Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care. JCO precision oncology 6 (2022)
Edwin Cuppen, Olivier Elemento, Richard Rosenquist, Svetlana Nikic, Maarten IJzerman, Isabelle Durand Zaleski, Geert Frederix, Lars-Åke Levin, Charles G Mullighan, Reinhard Buttner, Trevor J Pugh, Sean M Grimmond, Carlos Caldas, Fabrice Andre, Ilse Custers, Elias Campo, Hans van Snellenberg, Anna Schuh, Hidewaki Nakagawa, Christof von Kalle, Torsten Haferlach, Stefan Fröhling, Vaidehi Jobanputra
Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care. JCO precision oncology 6 (2022)
Edwin Cuppen, Olivier Elemento, Richard Rosenquist, Svetlana Nikic, Maarten IJzerman, Isabelle Durand Zaleski, Geert Frederix, Lars-Åke Levin, Charles G Mullighan, Reinhard Buttner, Trevor J Pugh, Sean M Grimmond, Carlos Caldas, Fabrice Andre, Ilse Custers, Elias Campo, Hans van Snellenberg, Anna Schuh, Hidewaki Nakagawa, Christof von Kalle, Torsten Haferlach, Stefan Fröhling, Vaidehi Jobanputra
Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care. JCO precision oncology 6 (2022)
Luan Nguyen, Myrthe Jager, Ruby Lieshout, Petra E de Ruiter, Mauro D Locati, Nicolle J M Besselink, Bastiaan R Van der Roest, Roel Janssen, Sander Boymans, Jeroen de Jonge, Jan Nicolaas Maria IJzermans, Michael Doukas, Monique M A Verstegen, Ruben van Boxtel, Luc J W van der Laan, Edwin Cuppen, Ewart W Kuijk
Precancerous liver diseases do not cause increased mutagenesis in liver stem cells. Communications biology 4 (1) (2021)
Mart M Lamers, Joep Beumer, Jelte van der Vaart, Kèvin Knoops, Jens Puschhof, Tim I Breugem, Raimond B G Ravelli, J Paul van Schayck, Anna Z Mykytyn, Hans Q Duimel, Elly van Donselaar, Samra Riesebosch, Helma J H Kuijpers, Debby Schipper, Willine J van de Wetering, Miranda de Graaf, Marion P G Koopmans, Edwin Cuppen, Peter J Peters, Bart L Haagmans, Hans Clevers
SARS-CoV-2 productively infects human gut enterocytes. Science (New York, N.Y.) 369 (6499) (2020)
Ewart W Kuijk, Myrthe Jager, Bastiaan R Van der Roest, Mauro D Locati, Arne Van Hoeck, Jerome Korzelius, Roel Janssen, Nicolle J M Besselink, Sander Boymans, Ruben van Boxtel, Edwin Cuppen
The mutational impact of culturing human pluripotent and adult stem cells. Nature communications 11 (1) (2020)
Sjors Middelkamp, Helena T A van Tol, Diana Carolina Johanna Spierings, Sander Boymans, Victor Guryev, Bernard A J Roelen, Peter M Lansdorp, Edwin Cuppen, Ewart W Kuijk
Sperm DNA damage causes genomic instability in early embryonic development. Science advances 6 (16) (2020)
Luan Nguyen, John W M Martens, Arne Van Hoeck, Edwin Cuppen
Pan-cancer landscape of homologous recombination deficiency. Nature communications 11 (1) (2020)
Ewart W Kuijk, Myrthe Jager, Bastiaan R Van der Roest, Mauro D Locati, Arne Van Hoeck, Jerome Korzelius, Roel Janssen, Nicolle J M Besselink, Sander Boymans, Ruben van Boxtel, Edwin Cuppen
Publisher Correction: The mutational impact of culturing human pluripotent and adult stem cells. Nature communications 11 (1) (2020)
Ewart W Kuijk, Francis Blokzijl, Myrthe Jager, Nicolle Besselink, Sander Boymans, Susana M Chuva de Sousa Lopes, Ruben van Boxtel, Edwin Cuppen
Early divergence of mutational processes in human fetal tissues. Science advances 5 (5) (2019)
Else Driehuis, Arne van Hoeck, Kat Moore, Sigrid Kolders, Hayley E Francies, M Can Gulersonmez, Edwin C A Stigter, Boudewijn Burgering, Veerle Geurts, Ana Gracanin, Gergana Bounova, Folkert H M Morsink, Robert Vries, Sylvia Boj, Johan van Es, G Johan A Offerhaus, Onno Kranenburg, Mathew J Garnett, Lodewyk Wessels, Edwin Cuppen, Lodewijk A A Brosens, Hans Clevers
Pancreatic cancer organoids recapitulate disease and allow personalized drug screening. Proceedings of the National Academy of Sciences of the United States of America (2019)
Sjors Middelkamp, Judith M Vlaar, Jacques Giltay, Jerome Korzelius, Nicolle Besselink, Sander Boymans, Roel Janssen, Lisanne de la Fonteijne, Ellen van Binsbergen, Markus J van Roosmalen, Ron Hochstenbach, Daniela Giachino, Michael E Talkowski, Wigard P Kloosterman, Edwin Cuppen
Prioritization of genes driving congenital phenotypes of patients with de novo genomic structural variants. Genome medicine 11 (1) (2019)
Sharon Christensen, Bastiaan R Van der Roest, Nicolle Besselink, Roel Janssen, Sander Boymans, John W M Martens, Marie-Laure Yaspo, Peter Priestley, Ewart W Kuijk, Edwin Cuppen, Arne Van Hoeck
5-Fluorouracil treatment induces characteristic T>G mutations in human cancer. Nature communications 10 (1) (2019)
Norman Sachs, Angelos Papaspyropoulos, Domenique D Zomer-van Ommen, Inha Heo, Lena Böttinger, Dymph Klay, Fleur Weeber, Guizela Huelsz-Prince, Nino Iakobachvili, Gimano D Amatngalim, Joep de Ligt, Arne Van Hoeck, Natalie Proost, Marco C Viveen, Anna Lyubimova, Luc Teeven, Sepideh Derakhshan, Jeroen Korving, Harry Begthel, Johanna F Dekkers, Kuldeep Kumawat, Emilio Ramos, Matthijs Fm van Oosterhout, G Johan Offerhaus, Dominique J Wiener, Eduardo P Olimpio, Krijn K Dijkstra, Egbert F Smit, Maarten van der Linden, Sridevi Jaksani, Marieke van de Ven, Jos Jonkers, Anne C Rios, Emile E Voest, Coline Hm van Moorsel, Cornelis K van der Ent, Edwin Cuppen, Alexander van Oudenaarden, Frank E Coenjaerts, Linde Meyaard, Louis J Bont, Peter J Peters, Sander J Tans, Jeroen S van Zon, Sylvia F Boj, Robert G Vries, Jeffrey M Beekman, Hans Clevers
Long-term expanding human airway organoids for disease modeling. The EMBO journal 38 (4) (2019)
Sander C Steenbeek, Thang V Pham, Joep de Ligt, Anoek Zomer, Jaco C Knol, Sander R Piersma, Tim Schelfhorst, Rick Huisjes, Raymond M Schiffelers, Edwin Cuppen, Connie R Jiménez, Jacco van Rheenen
Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. The EMBO journal 37 (15) (2018)
Francis Blokzijl, Roel Janssen, Ruben van Boxtel, Edwin Cuppen
MutationalPatterns: comprehensive genome-wide analysis of mutational processes. Genome medicine 10 (1) (2018)
Jarno Drost, Ruben van Boxtel, Francis Blokzijl, Tomohiro Mizutani, Nobuo Sasaki, Valentina Sasselli, Joep de Ligt, Sam Behjati, Judith E Grolleman, J Tom van Wezel, Serena Nik-Zainal, Roland P Kuiper, Edwin Cuppen, Hans Clevers
Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer. Science (New York, N.Y.) 358 (6360) (2017)
Arianna Fumagalli, Jarno Drost, Saskia J E Suijkerbuijk, Ruben van Boxtel, Joep de Ligt, G Johan Offerhaus, Harry Begthel, Evelyne Beerling, Ee Hong Tan, Owen J Sansom, Edwin Cuppen, Hans Clevers, Jacco van Rheenen
Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids. Proceedings of the National Academy of Sciences of the United States of America 114 (12) (2017)
Myrthe Jager, Francis Blokzijl, Valentina Sasselli, Sander Boymans, Roel Janssen, Nicolle Besselink, Hans Clevers, Ruben van Boxtel, Edwin Cuppen
Measuring mutation accumulation in single human adult stem cells by whole-genome sequencing of organoid cultures. Nature protocols 13 (1) (2017)
Frans Schutgens, Maarten B Rookmaaker, Francis Blokzijl, Ruben van Boxtel, Robert Vries, Edwin Cuppen, Marianne C Verhaar, Hans Clevers
Troy/TNFRSF19 marks epithelial progenitor cells during mouse kidney development that continue to contribute to turnover in adult kidney. Proceedings of the National Academy of Sciences of the United States of America 114 (52) (2017)
Marit W Vermunt, Sander C Tan, Bas Castelijns, Geert Geeven, Peter Reinink, Ewart de Bruijn, Ivanela Kondova, Stephan Persengiev, null null, Ronald Bontrop, Edwin Cuppen, Wouter de Laat, Menno P Creyghton
Epigenomic annotation of gene regulatory alterations during evolution of the primate brain. Nature neuroscience 19 (3) (2016)
Pjotr Prins, Joep de Ligt, Artem Tarasov, Ritsert C Jansen, Edwin Cuppen, Philip E Bourne
Toward effective software solutions for big biology. Nature biotechnology 33 (7) (2015)
Sebastian Schafer, Eleonora Adami, Matthias Heinig, Katharina E Costa Rodrigues, Franziska Kreuchwig, Jan Silhavy, Sebastiaan van Heesch, Deimante Simaite, Nikolaus Rajewsky, Edwin Cuppen, Michal Pravenec, Martin Vingron, Stuart A Cook, Norbert Hubner
Translational regulation shapes the molecular landscape of complex disease phenotypes. Nature communications 6 (2015)
Sarah Vergult, Ellen Van Binsbergen, Tom Sante, Silke Nowak, Olivier Vanakker, Kathleen Claes, Bruce Poppe, Nathalie Van der Aa, Markus J van Roosmalen, Karen Duran, Masoumeh Tavakoli-Yaraki, Marielle Swinkels, Marie-José van den Boogaard, Mieke M van Haelst, Filip Roelens, Frank Speleman, Edwin Cuppen, Geert Mortier, Wigard P Kloosterman, Björn Menten
Mate pair sequencing for the detection of chromosomal aberrations in patients with intellectual disability and congenital malformations. European journal of human genetics : EJHG 22 (5) (2013)

Edwin Cuppen.css-eqlu8i{font-size:small;padding-left:4px;} (E Cuppen)

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Edwin Cuppen (E Cuppen)