Mitracarpus frigidus reduces lipid metabolism and PGE2 levels in inflammatory cells.
Ari Sérgio de O LemosLara M CamposJuliana da T GranatoPriscila V Z C GoliattPaula R B DibEugenio D HottzNícolas GlanzmannLaíris C CamposHeloisa D S BizarroLuciana M ChedierElaine Soares CoimbraRodrigo Luiz FabriPublished in: The Journal of pharmacy and pharmacology (2023)
MFAq interferes with lipid metabolism in stimulated macrophages, leading to the reduction of important inflammatory mediators. Furthermore, MFAq can directly inhibit the COX-2 enzyme or inhibit its expression owing to its ability to reduce NO production.