Evaluation of the stability of ceftazidime/avibactam in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy utilizing a national stability protocol framework.
Saiyuri NaickerJason Alexander RobertsHayoung WonSteven C WallisSean UnwinConor JamiesonTim HillsMark GilchristMark SantilloR Andrew SeatonFelicity DrummondFekade Bruck SimePublished in: JAC-antimicrobial resistance (2024)
Whilst not meeting the strict UK YCD criteria for ≤5% degradation, ceftazidime/avibactam may be acceptable to administer as a continuous 12 hourly infusion in those territories where degradation of ≤10% is deemed acceptable.